Deans' stroke musings

Changing stroke rehab and research worldwide now.Time is Brain!Just think of all the trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group.
My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html

Monday, July 31, 2017

Novel Device Shows Promise for Early Identification of Serious Strokes

I see nothing here that compared this to other fast diagnosis possibilities. So further research is once again required which will never occur, you will continue to be screwed until we get a great stroke association.  Notice time of seconds to diagnose and no neurologist needed.

Hats off to Helmet of Hope - stroke diagnosis in 30 seconds

 

Microwave Imaging for Brain Stroke Detection and Monitoring using High Performance Computing in 94 seconds

 

New Device Quickly Assesses Brain Bleeding in Head Injuries - 5-10 minutes

http://www.prnewswire.com/news-releases/novel-device-shows-promise-for-early-identification-of-serious-strokes-300494693.html
Results of the VITAL study presented as a Late Breaker at the 14th Annual Meeting of The Society of NeuroInterventional Surgery demonstrate how a new technology may change the paradigm of emergency stroke care.
News provided by
Cerebrotech Medical Systems
Jul 26, 2017, 14:21 ET

PLEASANTON, Calif., July 26, 2017 /PRNewswire/ -- Cerebrotech Medical Systems, an innovative medical device company focused on the development of portable neurotechnology solutions, today reported results from a new study evaluating its proprietary VIPS™ technology for emergency stroke patients. The results of the study, VITAL, which are being presented at the 14th Annual Meeting of The Society of NeuroInterventional Surgery in Colorado Springs, CO, demonstrate that Cerebrotech's non-invasive, visor-like neurological device can identify those patients with large vessel occlusion (LVO) strokes and large hemorrhagic strokes versus those with less urgent strokes, allowing for earlier intervention to prevent further brain damage. 
"This multi-center clinical trial shows the viability of a non-invasive technology that can quickly identify treatable devastating strokes in ambulances or emergency rooms to enable rapid triage those patients to specialized, capable treatment centers, thereby saving lives," said Christopher P. Kellner, M.D., Director of the Intracerebral Hemorrhage Program at Mount Sinai and Assistant Professor of Neurosurgery at the Icahn School of Medicine at Mount Sinai. "This trial demonstrates that Cerebrotech's device has the potential to do for stroke what EKG has done for heart attack."
Dr. Kellner presented data demonstrating that Cerebrotech's device is capable of differentiating large strokes from small strokes with sensitivity of 93% (95% CI 83-98) and specificity of 92% (95% CI 75-99). Comparison of large strokes to healthy adults yielded 100% specificity. Importantly, Kellner's presentation also demonstrated the underlying reasons why the device offers this level of accuracy.  The data show that subjects with large strokes (55 ischemic and 2 hemorrhagic) have significantly higher bioimpedance asymmetry, a measure of the electrical characteristics of the brain, compared to those with small strokes (16 ischemic and 10 hemorrhagic) that do not require emergent triage to special centers. Large stroke subjects had an average asymmetry score of 16.5% (95% CI 14.6-18.4), versus those with small strokes, which had an average asymmetry score of 8.0% (95% CI 6.9-9.0, p<0.0001). Average bioimpedance asymmetry in a cohort of 79 healthy adults was 5.0% (95% CI 4.5-5.5).  By measuring bioimpedance asymmetry, the device is able to identify stroke and differentiate large strokes from small strokes.
The presented data consisted of: the VITAL study (N=128), which evaluated patients presenting with a range of brain injuries including strokes and was conducted by a group that included distinguished researchers from Icahn School of Medicine at Mount Sinai (New York City), The Medical University of South Carolina, Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, and Baptist Medical Center Jacksonville; an initial pilot study (N=41) conducted at The Medical University of South Carolina; and a study of healthy volunteers for baseline comparators. The data were managed by Vastrax, a first-of-its kind neurovascular clinical research and development partner.
"There is a critical, highly-visible unmet need for effective, early stroke assessment in ambulances and emergency rooms to identify which patients need triage directly to specialty stroke hospitals for immediate surgical intervention," said Mitch Levinson, President and CEO, Cerebrotech Medical Systems. "By helping to minimize treatment delays, this technology has the potential to substantially improve healthcare outcomes for hundreds of thousands of people each year across the globe."
Cerebrotech's technology, Volumetric Integral Phase-shift Spectroscopy (VIPS), passes low-energy electromagnetic waves through the brain, detecting small changes to the brain's electrical properties. These electrical characteristics, called bioimpedance, are related to brain tissue and fluid status, and asymmetries can be indicative of clinical problems. Quantitative results provided by the device can be obtained in seconds by medical professionals after minimal training, and the simple device design allows results to be obtained without interfering with any aspect of patient care. The device holds a CE mark, but is not yet cleared for sale in the U.S.
Early detection of brain injury means early intervention, which can greatly improve patient outcomes and transform the management paradigm of these life-threatening neurological events. Every 45-minute reduction in time to thrombectomy, the new standard of care for large vessel occlusion strokes, yields a 10% increase in the number of patients achieving functional independence at 3 months.
The Society of NeuroInterventional Surgery (SNIS), a worldwide scientific and educational association, is dedicated to excellence in comprehensive, minimally-invasive care of patients with stroke, brain aneurysms, and other diseases in the head, neck and spine. SNIS draws its membership from three areas - interventional neuroradiology, endovascular neurosurgery and interventional neurology. 
About Cerebrotech Medical SystemsCerebrotech Medical Systems, Inc., is a venture capital-backed company dedicated to designing neurotechnology solutions to improve the care of brain-injured patients worldwide. The company is developing a portable, noninvasive neuro-monitoring device that allows for earlier detection of potentially life-threatening conditions such as large vessel occlusion stroke, cerebral edema, traumatic brain injury, and others. Founded in 2010 and based in Pleasanton, CA, Cerebrotech's core intellectual property is licensed exclusively from the University of California at Berkeley. For more information, visit www.cerebrotechmedical.com.
1 Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis. JAMA. 2016;316(12):1279-1288. doi:10.1001/jama.2016.13647

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