Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, February 7, 2018

Low-calorie diets impair cardiac function, increase myocardial lipids

You'll have to ask your doctor  how this compares to your diet protocol and intermittent fasting.
https://www.healio.com/cardiology/imaging/news/online/%7B76c9555b-0898-43e1-a80d-624bf1254d34%7D/low-calorie-diets-impair-cardiac-function-increase-myocardial-lipids?
In patients with obesity who consumed a very low-calorie diet for 7 days, cardiac function declined and myocardial fat accumulated, according to an abstract presented at CMR 2018.
The diet also improved whole-body insulin sensitivity and hepatic fat, researchers reported.
“The metabolic improvements with a very low-calorie diet, such as a reduction in liver fat and reversal of diabetes, would be expected to improve heart function,” Jennifer J. Rayner, BMBCh, MRCP(UK), clinical research fellow at the Oxford Centre for Clinical Magnetic Resonance at University of Oxford in the United Kingdom, said in a press release. “Instead, heart function got worse in the first week before starting to improve.”
Researchers analyzed data from 21 patients with obesity (mean age, 52 years; 6 men; mean BMI, 37.1 kg/m2) who were on a very low-calorie diet for 8 weeks. Patients consumed between 600 kcal and 800 kcal daily.
Tests were conducted 1 week before, 1 week after and 8 weeks after the diet was initiated, which included an MRI for liver fat and abdominal visceral fat quantification, an echocardiogram to analyze diastolic function and spectroscopy to measure myocardial triglyceride content. Left ventricle structure and function were also reviewed.
At 7 days, visceral fat decreased by 11% (P = .005), total body fat fell by 6% (P < .001) and hepatic fat decreased by 42% (P < .001), whereas insulin resistance (P = .005), triglycerides (P < .01), fasting total cholesterol (P < .01) and glucose improved (P < .01).
Myocardial triglyceride content increased by 44% (P = .038) after 1 week, which led to reductions in systolic (P = .032) and diastolic function (P = .024). This increase was also associated with a change in LV ejection fraction (P = .05) and diastolic function (P = .058).
At 8 weeks, myocardial triglyceride content and cardiac function returned to normal as peripheral metabolic measurements improved from baseline.
“This suggests that although these diet programs are highly effective, they are likely to require careful monitoring in the early stages in individuals with cardiac disease,” Rayner and colleagues wrote. – by Darlene Dobkowski
Reference:
Rayner JJ, et al. Abstract P084. Presented at: CMR 2018; Jan. 31-Feb. 3, 2018; Barcelona, Spain.

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