Deans' stroke musings: Association of coffee consumption and non-motor symptoms in drug-naïve, early-stage Parkinson's disease

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Friday, February 23, 2018

Association of coffee consumption and non-motor symptoms in drug-naïve, early-stage Parkinson's disease

With your chance of getting Parkinsons post stroke and this news my choice of massive coffee consumption seems warranted. But don't listen to me, I'm not medically trained. Of course no amounts are given, so you'll have to guess.

Parkinson’s Disease May Have Link to Stroke

How coffee protects against Parkinson’s Aug. 2014

http://www.prd-journal.com/article/S1353-8020(18)30052-X/fulltext?rss=yes

Bang-Hoon Cho

Seong-Min Choi

Correspondence information about the author Seong-Min Choi

Email the author Seong-Min Choi

Joon-Tae Kim

Byeong C. Kim

PlumX Metrics

DOI: https://doi.org/10.1016/j.parkreldis.2018.02.016

Article Info

Highlights

•There is an inverse association between coffee consumption and non-motor symptoms (NMSs) of drug-naïve PD patients.
•Coffee drinkers had a lower severity in several sub-items of the mood/cognition domain compared to non-coffee drinkers.
•It is important to consider the history of coffee consumption in the assessment of NMSs of PD patients.

Abstract

Objective

Coffee consumption has an inverse association with the risk of Parkinson's disease (PD). The aim of this study was to investigate the association between coffee consumption and non-motor symptoms (NMSs) in patients with PD.

Methods

In this cross-sectional study, we included 196 early-stage, treatment-naïve PD patients. Coffee consumption history was obtained via semi-structured interviews. NMSs were assessed using the Non-Motor Symptom assessment scale (NMSS).

Results

Of the 196 patients with PD, 136 (69.3%) were categorized as coffee drinkers and 60 (30.6%) were non-drinkers. Coffee drinkers were younger, predominantly male, were younger in age at symptom onset, had lower Unified Parkinson's Disease Rating Scale motor and Beck Depression Inventory scores, and higher Mini-Mental State Examination scores than non-coffee drinkers. After adjustment, coffee drinking was significantly inversely associated with the prevalence of lack of motivation, anhedonia, and lack of pleasure, which were less frequent in coffee drinkers. Total NMSS scores were lower in coffee drinkers than in non-drinkers (p = 0.047). In particular, coffee drinking was significantly associated with a reduced severity of the mood/cognition domain of NMSS (p = 0.003). After correcting for multiple testing, there were no significant differences in the prevalence of NMSs, but there were significant differences in the severity of NMSs between coffee drinkers and non-drinkers.

Conclusion

There is a negative association between coffee consumption and the severity of the mood/cognition domain of NMSS in patients with PD. Clinicians should consider the history of coffee consumption in the assessment of NMSs in PD.