Deans' stroke musings: A Neuroanatomical Framework for Upper Limb Synergies after Stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, October 22, 2019

A Neuroanatomical Framework for Upper Limb Synergies after Stroke

Use of the word 'may' 4 times tells me nothing useful comes out of this to get survivors recovered. We need; do this and you get this result. WHEN THE HELL WILL YOU PROVIDE THAT?

A Neuroanatomical Framework for Upper Limb Synergies after Stroke

Angus J. C. McMorland , Keith D. Runnalls and Winston D. Byblow *
Movement Neuroscience Laboratory, Department of Sport and Exercise Science, Centre for Brain Research,The University of Auckland, Auckland, New Zealand
Edited by:
Ana Bengoetxea, Universidad del País Vasco-Euskal Herriko Unibertsitatea,Spain
Reviewed by:
Jean-LouisThonnard, Université Catholique de Louvain, BelgiumAaron Batista, University of Pittsburgh, USA
*Correspondence:
Winston D. Byblow, Movement Neuroscience Laboratory,Department of Sport and Exercise Science, Centre for Brain Research,The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand e-mail: w.byblow@auckland.ac.nz
Muscle synergies describe common patterns of co- or reciprocal activation that occur during movement. After stroke, these synergies change, often in stereotypical ways.The mechanism underlying this change reﬂects damage to key motor pathways as a result ofthe stroke lesion, and the subsequent reorganization along the neuroaxis, which may be further detrimental or restorative to motor function.The time course of abnormal synergy formation seems to lag spontaneous recovery that occurs in the initial weeks after stroke.In healthy individuals, motor cortical activity, descending via the corticospinal tract (CST)is the predominant driver of voluntary behavior. When the CST is damaged after stroke,other descending pathways may be up-regulated to compensate.The contribution of these pathways may emerge as new synergies take shape at the chronic stage after stroke, as a result of plasticity along the neuroaxis.The location of the stroke lesion and properties ofthe secondary descending pathways and their regulation are then critical for shaping thesynergies in the remaining motor behavior. A consideration of the integrity of remaining descending motor pathways may aid in the design of new rehabilitation therapies.