We have been told time and time again that it is better to get supplements from natural sources. So it is really discouraging that they ignored an easy generally available source; red wine. No results yet even though the study ended Nov. 1, 2020.
- Nebbiolo. The Nebbiolo grape is, in many ways, Italy's prized possession. ...
- Cabernet Sauvignon. If there's one grape that most people are familiar with as being tannic, it's Cabernet Sauvignon. ...
- Syrah. ...
- Monastrell. ...
- Sangiovese. ...
- Montepulciano. ...
- Malbec.
The latest here:
Tannin Specific Natural Extract for COVID-19 Infection (TanCOVID)
| Condition or disease | Intervention/treatment | Phase |
|---|---|---|
| COVID-19 SARS-CoV 2 Coronavirus Infection | Dietary Supplement: ARBOX Other: PLACEBO | Not Applicable |
The epidemic of 2019 novel coronavirus (causing the disease Covid-19) has expanded from Wuhan throughout China and is being exported to a growing number of countries, some of which have seen onward transmission. COVID-19 caused clusters of severe respiratory illness and was associated with 2% mortality. There is currently no vaccine and no specific antiviral treatment recommended for COVID-19. About 20% of the patients were severe and the mainstay of clinical management is largely symptomatic treatment, with organ support in intensive care for seriously ill patients. Therefore, it is urgent to find a safe and effective therapeutic approach to COVID-19.
Tannins have been shown to have antioxidant, anti-inflammatory, antimicrobial properties and a regulatory effect on the gastrointestinal metabolism.
The investigators will realize a prospective, double-blind, randomized trial to assess the effect of treatment with a dietary supplement (ARBOX), a molecular complex of quebracho and chestnut tannins extract and Vit B12, compared with placebo. 140 COVID-19 patients will be recruited in a single center in Buenos Aires Argentina. 70 patients will receive conventional treatment plus ARBOX (treated group) and 70 patients will receive conventional treatment plus placebo (control group). The effects will be evaluated during the 28 days follow up. The primary end point will be the time of discharge from the hospital. A panel of 27 cytokines level, intestinal microbiota composition and its metabolites will be assessed at day 1 and 14.
| Study Type : | Interventional (Clinical Trial) |
| Actual Enrollment : | 124 participants |
| Allocation: | Randomized |
| Intervention Model: | Parallel Assignment |
| Masking: | Triple (Participant, Care Provider, Investigator) |
| Primary Purpose: | Treatment |
| Official Title: | Efficacy of Tannin Specific Natural Extract for Coronavirus Disease (COVID-19): Randomized Controlled Trial |
| Actual Study Start Date : | June 12, 2020 |
| Actual Primary Completion Date : | October 20, 2020 |
| Actual Study Completion Date : | November 1, 2020 |
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