Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, July 8, 2026

Neuronal migration into injured tissue: mechanisms and therapeutic strategies for brain regeneration

 How will your competent? doctor PRECISELY USE THIS TO MIGRATE NEURONS TO WHERE THEY ARE NEEDED POST STROKE?

And then initiate dendritic branching and axon pathfinding to connect everything up! NO clue! COMPLETE FUCKING INCOMPETENCE, get them fired, it means they have not had one complete thought on stroke recovery ever!

Neuronal migration into injured tissue: mechanisms and therapeutic strategies for brain regeneration


Author links open overlay panel
a
Department of Developmental and Regenerative Neurobiology, Institute of Brain Science (IBS), Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
b
Division of Neural Development and Regeneration, National Institute for Physiological Sciences (NIPS), Okazaki, Japan

Highlights

  • New neurons generated in the V-SVZ migrate in the intact and injured brain by regulating cytoskeletal dynamics.
  • New neurons migrate to the injured region and replace lost neurons, contributing to the recovery of motor and sensory functions.
  • Biomaterials and pharmacological approaches that promote neuronal migration toward injured regions are being actively investigated and may lead to fundamental therapies for brain injury.

Abstract

Neuronal migration is a crucial process not only for brain development but also for neural regeneration after injury. It has been reported that some new neurons generated in the ventricular-subventricular zone (V-SVZ) migrate toward tissue injured by ischemic stroke and other forms of brain damage. These migrating neurons can partially compensate for lost neurons and contribute to functional recovery, including improvements in motor function. Therefore, understanding the mechanisms that regulate neuronal migration is expected to facilitate the development of novel therapeutic strategies that enhance endogenous neural regeneration after brain injury.
In this review, we discuss the migratory mechanisms of new neurons generated in the V-SVZ and summarize current insights into strategies aimed at promoting neuronal migration and neuronal replacement in the injured brain.

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