Deans' stroke musings: Revolutionary New Project Will Obtain Complete Genetic Information on Largest Group for a Single Disease

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, July 2, 2012

Revolutionary New Project Will Obtain Complete Genetic Information on Largest Group for a Single Disease — Alzheimer's

Where is the similar initiative for stroke? If we are having such a hard time getting to recovery, prevention is the solution.
WSO - Bo Norrving
ASA - Dr. Gordon F. Tomaselli
NSA - Jim Baranski

http://act.alz.org/site/R?i=5q2a-IuUcaWG6gfxSNeNfw

The first, pioneering “Big Data” project for Alzheimer’s disease was announced today by a visionary new partnership. New research funding from the Alzheimer’s Association and the Brin Wojcicki Foundation will enable scientists to obtain whole genome sequences on the largest group of individuals related to a single disease – more than 800 people enrolled in the Alzheimer’s Disease Neuroimaging Initiative (ADNI).

“The movement to find preventions and a cure for Alzheimer’s will soon take a significant step forward,” said Harry Johns, Alzheimer’s Association President and CEO. “This new initiative will rapidly create an unprecedented tool for researchers to create a world without Alzheimer’s.”

The goal of ADNI is to identify and understand markers of Alzheimer’s disease in body fluids, structural changes in the brain, and measures of memory; the hope is to improve early diagnosis and accelerate the discovery of new treatments. Whole genome sequencing determines all 6 billion letters in an individual's DNA in one comprehensive analysis. Scientific leaders directing this project emphasize the potentially groundbreaking importance of the ability to match existing data from ADNI with the newly-generated gene sequence data.

A distinguishing feature of ADNI is that its research data are made freely available without delay to scientists around the globe. Once the genome sequences are completed – roughly 16 weeks after the sequencing project starts – the raw data will rapidly be made available to qualified scientists worldwide. Leveraging the power of global collaboration, researchers will be able to mine the data for novel targets for risk assessment, new therapies and much-needed insight into the causes of the devastating brain disease.

This new project is a significant extension of ADNI, which is a public-private research project led by the National Institutes of Health (NIH) and funded with private sector support. Launched in 2004, ADNI’s public-private funding consortium includes pharmaceutical companies, science-related businesses and nonprofit organizations including the Alzheimer’s Association.

The Brin Wojcicki Foundation was established by Sergey Brin, the co-founder of Google, and Anne Wojcicki, the co-founder of 23andMe, a leading personal genetics company.

Ridding the world of Alzheimer’s disease is a global challenge of the utmost importance. Together with our partners, the Association is taking an important new step with this investment.