So have our researchers apply the same idea to common damage areas, motor, sensory, language. If we don't know how this works how will we ever come up with a therapy to correct it?
Neurocognitive Brain Response to Transient Impairment of Wernicke's Area
Abstract
This study examined how the brain system
adapts and reconfigures its information processing capabilities to
maintain cognitive
performance after a key cortical center [left
posterior superior temporal gyrus (LSTGp)] is temporarily impaired
during the
performance of a language comprehension task. By
applying repetitive transcranial magnetic stimulation (rTMS) to LSTGp
and
concurrently assessing the brain response with
functional magnetic resonance imaging, we found that adaptation
consisted of
1) increased synchronization between compensating
regions coupled with a decrease in synchronization within the primary
language
network and 2) a decrease in activation at the rTMS
site as well as in distal regions, followed by their recovery. The
compensatory
synchronization included 3 centers: The
contralateral homolog (RSTGp) of the area receiving rTMS, areas adjacent
to the rTMS
site, and a region involved in discourse monitoring
(medial frontal gyrus). This approach reveals some principles of
network-level
adaptation to trauma with potential application to
traumatic brain injury, stroke, and seizure.
No comments:
Post a Comment