Deans' stroke musings: Unstoppable menstruation induced by the concomitant use of tizanidine and warfarin

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, January 31, 2013

Unstoppable menstruation induced by the concomitant use of tizanidine and warfarin

Women, be careful out there.
http://www.cadrj.com/qikan/epaper/zhaiyao.asp?bsid=17703

Abstract

A 51-year-old woman with rheumatic heart disease and cerebral embolism received warfarin for about one year and the dosage was reduced gradually from 2.25 mg/d to 1.5 mg/d. At the same time, she was given tizanidine 2 mg thrice daily (2 mg twice daily at the first week)because of her right upper limb spasticity. About 20 days later, her menstruation started and lasted more than 20 days. Tizanidine was withdrawn and, 5-6 days later, her menstruation stopped. Laboratory examination showed the following results: prothrombin time 19.5 s, prothrombin activity 64.9%, prothrombin time ratio 1.56, international normalized ratio 1.61, partial thromboplastin time 37.2 s, thromboplastin time 13.5 s, fibrinogen 3.8 g/L. Warfarin was continued at the same dose as before. The situation of prolonged menstrual period and increased menstrual flow did not reccur at a one-year follow-up.