Get your researchers after this, this sounds incredibly important.
http://livasperiklis.com/2013/07/02/httpwp-mep29tmj-4hs/
Researchers at NYU Langone Medical Center have discovered a mechanism that triggers chronic inflammation in Alzheimer’s, atherosclerosisand type-2 diabetes.
The
results, published today in Nature Immunology, suggest a common
biochemical thread to multiple diseases and point the way to a new class
of therapies that could treat chronic inflammation in these
non-infectious diseases without crippling the immune system.
Alzheimer’s, atherosclerosis and type-2 diabetes—diseases associated
with aging and inflammation—affect more than 100 million Americans.
When the body encounters a
pathogen, it unleashes a rush of chemicals known as cytokines that draws
immune cells to the site of infection and causes inflammation.
Particulate matter in the body, such as the cholesterol crystals
associated with vascular disease and the amyloid plaques that form in
the brain in Alzheimer’s disease, can also cause inflammation but the
exact mechanism of action remains unclear. Researchers previously
thought that these crystals and plaques accumulate outside of cells, and
that macrophages—immune cells that scavenge debris in the body—induce
inflammation as they attempt to clear them.
“We’ve discovered that the mechanism causing chronic inflammation in these diseases is actually very different,” says Kathryn J. Moore, PhD,
senior author of the study and associate professor of medicine and cell
biology, Leon H. Charney Division of Cardiology at NYU Langone Medical
Center.
More at link.
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