Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, November 14, 2015

Every 67 Seconds: Genetics in Alzheimer’s Disease

Every 40 seconds someone has a stroke and yet our fucking failures of stroke associations can't get stroke front and center in the publics' consciousness and get research dollars allocated to solve all the problems in stroke. And the reason for that is because they refuse to publicly state that everything in stroke is a failure. All you get from them is 'Happy talk'.  Fucking worthless pieces of shit.
http://danablog.org/2015/11/13/every-67-seconds-genetics-in-alzheimers-disease/
Genes passed down from generation to generation within families are the main culprit in contracting Alzheimer’s disease. Recent research for the disease is focusing on individual variations of these genes, instead of trying to find a “one size fits all” treatment.
That was part of the message delivered by Richard Mayeux, the Gertrude H. Sergieysky co-director of the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain at Columbia University Medical Center. Mayeux’s talk on the role that genetics plays in Alzheimer’s disease last Thursday evening at the 92nd Street Y in Manhattan came at an opportune time. November is both National Alzheimer’s Disease Awareness month and National Epilepsy Awareness Month.
Mayeux, M.D., MS.c., who is also Professor of Neurology, Psychiatry, and Epidemiology and a member of the Dana Alliance for Brain Initiatives, has been featured in the New York Academy of Sciences podcast series, Dementia Decoded. His research on genomes aims to understand the differences in gene structure and what it could mean for future treatment.

Through the use of genome-wide association studies, Mayeux and his colleagues are examining common genetic variants to see if any variant is associated with the traits common to the disease. (See more about the gene involvement in the brain in our Brain in the News article, Genetics and the Brain.) Mayeux believes that developing successful treatments will depend on better understanding genetic and environmental influences. His research team has learned that treatment will be tied to each patient’s individual genetic profile and specific gene structure. Mayeux outlined examples of individuals with varying levels of APOe, a protein that is heavily involved in Alzheimer’s, and the different ways that it influences how each individual processes amyloid. Factors such as these, as well as many others, make each patient unique. He described future treatment for the disease as “precision medicine,” such as the way cancers, brain tumors, etc., are cared for.
Mayeux said that he and other specialists submit their research findings and family studies to a large database open to all qualified scientists. With the Obama Administration’s $50 million reallocation towards Alzheimer’s research, funds have been committed to study the genome in more detail, and the use of Mayeux’s and other scientists’ datasets will help in conducting more accurate analyses. In the Q&A, Mayeux expressed his enthusiasm for a breakthrough and the renewed pharmaceutical interest –
“I’m more than halfway through my career – and I’ve never been more excited.”
With life spans expanding due to advances in almost every other area of medicine, Mayeux’s research is vital to the future of the nation’s healthcare system. According to the Alzheimer’s Association, about 5.3 million people (7 million in the US have survived a stroke) in the United States suffer from Alzheimer’s disease, and a new person is diagnosed every 67 seconds. Heathcare costs to treat the disease in 2015 are estimated at more than $200 billion. (Without Action, Financial Cost of Strokes to Reach $2.2 Trillion by 2050)
To see Richard Mayeux and other specialists speak more about Alzheimer’s disease, check out the Dana Foundation’s YouTube playlist, Dana Alliance Experts on Dementia/Alzheimer’s Disease.

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