Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, December 17, 2015

Trajectory of Cognitive Decline After Incident Stroke

In spite of my doctor doing nothing for my cognition or physical effects of the stroke I actually feel smarter and more focused post-stroke. A likely outlier, one of those who should be studied to see why and how to replicate. What is your doctor doing to measure and document your cognitive status and decline? Mine did nothing.
Scientists from the University of Michigan have found that preventing a stroke keeps your mind 8 years younger and sharper. 
http://www.ncbi.nlm.nih.gov/pubmed/26151265

Author information

  • 1Department of Internal Medicine, University of Michigan Medical School, Ann Arbor2Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan3Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor4Department of.
  • 2Department of Internal Medicine, University of Michigan Medical School, Ann Arbor5Department of Biostatistics, University of Michigan, Ann Arbor.
  • 3Department of Internal Medicine, University of Michigan Medical School, Ann Arbor2Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan3Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor6Institute for.
  • 4Department of Psychiatry, Indiana University of School of Medicine, Indianapolis.
  • 5Department of Internal Medicine, University of Michigan Medical School, Ann Arbor2Veterans Affairs Center for Clinical Management Research, Ann Arbor, Michigan.
  • 6Department of Psychiatry, University of Michigan Medical School, Ann Arbor.
  • 7Department of Medicine, University of Alabama at Birmingham School of Medicine.

Abstract

IMPORTANCE:

Cognitive decline is a major cause of disability in stroke survivors. The magnitude of survivors' cognitive changes after stroke is uncertain.

OBJECTIVE:

To measure changes in cognitive function among survivors of incident stroke, controlling for their prestroke cognitive trajectories.

DESIGN, SETTING, AND PARTICIPANTS:

Prospective study of 23,572 participants 45 years or older without baseline cognitive impairment from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort, residing in the continental United States, enrolled 2003-2007 and followed up through March 31, 2013. Over a median follow-up of 6.1 years (interquartile range, 5.0-7.1 years), 515 participants survived expert-adjudicated incident stroke and 23,057 remained stroke free.

EXPOSURE:

Time-dependent incident stroke.

MAIN OUTCOMES AND MEASURES:

The primary outcome was change in global cognition (Six-Item Screener [SIS], range, 0-6). Secondary outcomes were change in new learning (Consortium to Establish a Registry for Alzheimer Disease Word-List Learning; range, 0-30), verbal memory (Word-List Delayed Recall; range, 0-10), and executive function (Animal Fluency Test; range, ≥0), and cognitive impairment (SIS score <5 [impaired] vs ≥5 [unimpaired]). For all tests, higher scores indicate better performance.

RESULTS:

Stroke was associated with acute decline in global cognition (0.10 points [95% CI, 0.04 to 0.17]), new learning (1.80 points [95% CI, 0.73 to 2.86]), and verbal memory (0.60 points [95% CI, 0.13 to 1.07]). Participants with stroke, compared with those without stroke, demonstrated faster declines in global cognition (0.06 points per year faster [95% CI, 0.03 to 0.08]) and executive function (0.63 points per year faster [95% CI, 0.12 to 1.15]), but not in new learning and verbal memory, compared with prestroke slopes. Among survivors, the difference in risk of cognitive impairment acutely after stroke, compared with immediately before stroke, was not statistically significant (odds ratio, 1.32 [95% CI, 0.95 to 1.83]; P = .10); however, there was a significantly faster poststroke rate of incident cognitive impairment compared with the prestroke rate (odds ratio, 1.23 per year [95% CI, 1.10 to 1.38]; P < .001). For a 70-year-old black woman with average values for all covariates at baseline, stroke at year 3 was associated with greater incident cognitive impairment: absolute difference of 4.0% (95% CI, -1.2% to 9.2%) at year 3 and 12.4% (95% CI, 7.7% to 17.1%) at year 6.

CONCLUSIONS AND RELEVANCE:

Incident stroke was associated with an acute decline in cognitive function and also accelerated and persistent cognitive decline over 6 years.

1 comment:

  1. While my cognitive abilities were pathetic immediately after the stroke, my husband says I've recovered a lot, but am still not as smart as I used to be. I did correctly factor a simple quadratic equation a few days after having a stroke, and I've improved a lot since then, but I'm still not smart enough, in his opinion?

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