Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, December 21, 2015

Stroke Recovery Better With Ambien: Study - In mice

I don't remember if I got Ambien or Lunesta as a sleeping pill while in the hospital. If it did any good it didn't really show. Once again this will not have a followup study in humans because we have NO stroke strategy or stroke leadership. Your children and grandchildren are going to still be screwed if they have a stroke if we don't remove existing stroke leadership. You'll have to read the study in Brain to see what functional changes there were. 
http://www.latinoshealth.com/articles/14026/20151220/stroke-recovery-better-ambien-study.htm
This is proven and tested in mice. A sleeping pill is revealed to have properties that can help stroke patients recover.
In a study, a low dose of sleeping aid called Zolpidem, also known as Ambien, was given to mice. Zolpidem was used to cure insomnia.
The study aims to discover faster recovery therapeutics for ischaemic stroke. Researchers, who are from Stanford University School of Medicine, had successfully found the faster way after testing it on mice.
Published in the journal Brain, the study noted that it would usually take days, up to months to recover.
Long and certain methods were done to achieve the aim of the research study. Three to five mice were placed inside a cage under normal conditions. Mice, which were 10 to 30 weeks old, were anesthetized with isoflurane (2.5 percent in a mixture of 1 l/min of air and 0.2 l/min of oxygen). Body temperature was measured by rectal probe. No deaths were recorded.
Skin incisions were done to sham animals to expose the distal middle cerebral artery and Photothrombotic model. In the second day of the experiment, another anesthesia and cuts to the mice carried out.
They were also stained with 2 percent triphenyltetrazolium chloride (TTC). This was done again in days 7 and 28, only using heparinized phosphate-buffered saline and paraformaldehyde to spread in the tissue, and stained with Cresyl violet at day 28.
Array tomography was done after a series of stroke models. According to Smithlab, array tomography is a new proteometric method in imaging that gives out high-resolution of tissue molecular images. The Gamma-Aminobutyric acid (GABA) synapses were then analyzed.

GABA, as stated in The Brain, is a neurotransmitter that serves as the distributor of chemicals in the brain. The researchers had only included "stroke-injured animals with lesions with a medial edge within 3.0 ± 0.3 mm from the midline" for analysis. Whole-cell patch-clamp techniques were also used to analyze the synapses.
After a long process and further analysis, the researchers have concluded that GABA signaling using a low dose of Zolpidem can help stroke patients recover faster. According to them, Zolpidem enhances functional recovery in just four days.
While the results of the study are beneficial for stroke recovery, Science Daily said co-researcher Gary Steinberg suggests to make further studies in other laboratories before starting to use Ambien in stroke recovery.

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