Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 27,818 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain!trillions and trillions of neuronsthatDIEeach day because there areNOeffective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.
Friday, December 18, 2015
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
Your doctor should put this post and the previous one on DMB together to create a stroke prevention protocol. You'll have to hope your doctor is the genius one that can do this right the first time. OR we could ask our fucking failures of stroke associations to fail once again at translating research into protocols. But since none of them have an entry point for survivors that won't work at all.
Metabolomics studies hold promise for the discovery of
pathways linked to disease processes. Cardiovascular disease (CVD)
represents the leading cause of death and morbidity worldwide. Here we
used a metabolomics approach to generate unbiased small-molecule
metabolic profiles in plasma that predict risk for CVD. Three
metabolites of the dietary lipid phosphatidylcholine—choline,
trimethylamine N-oxide (TMAO) and betaine—were identified and
then shown to predict risk for CVD in an independent large clinical
cohort. Dietary supplementation of mice with choline, TMAO or betaine
promoted upregulation of multiple macrophage scavenger receptors linked
to atherosclerosis, and supplementation with choline or TMAO promoted
atherosclerosis. Studies using germ-free mice confirmed a critical role
for dietary choline and gut flora in TMAO production, augmented
macrophage cholesterol accumulation and foam cell formation. Suppression
of intestinal microflora in atherosclerosis-prone mice inhibited
dietary-choline-enhanced atherosclerosis. Genetic variations controlling
expression of flavin monooxygenases, an enzymatic source of TMAO,
segregated with atherosclerosis in hyperlipidaemic mice. Discovery of a
relationship between gut-flora-dependent metabolism of dietary
phosphatidylcholine and CVD pathogenesis provides opportunities for the
development of new diagnostic tests and therapeutic approaches for
atherosclerotic heart disease.
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