Pickering A, Harnan S, Cooper K, et al. Acute
ischaemic stroke patients - direct admission to a specialist centre or
initial treatment in a local hospital? A systematic review Journal of Health Services Research & Policy. 2015 May.
Review question
Are
mortality rates decreased when stroke patients bypass local,
non-specialist hospitals in favour of specialist stroke centres?
Background
Treating
patients with a suspected stroke is a time-critical concern, and there
is uncertainty regarding the benefit of directly transferring patients
to a specialist stroke centre rather than beginning therapy at a local,
non-specialist hospital.
Current
guidelines recommend that stroke patients be admitted directly to
stroke centres, but therapy can begin in a local, non-specialist
hospital under appropriately trained staff before transfer to a
specialist centre.
Due
to the time-sensitive nature of treating someone who has had a stroke,
the best treatment option may be at the closest, local hospital.
How the review was done
A
detailed search of a number of electronic databases for studies
published from 1988 to 2012 was conducted. Studies that compared direct
admission of stroke patients to a specialist centre with admission of
stroke patients to a non-specialist centre (with the potential to
transfer), were included in the review.
A total of 14 studies were included in the review after assessment for eligibility.
This review was funded by the National Institute for Health Research Service Delivery and Organization Programme.
What the researchers found
The
review found that stroke mortality rates were no different when
patients began therapy at local hospitals and then transferred to stroke
centres, as compared to direct admission to a stroke centre.
When
patients were assessed for complications after discharge from the
hospital, outcomes were the same for those who transferred directly to a
stroke centre and those who transferred from a local hospital.
The
included studies showed that there is uncertainty as to whether time to
therapy is longer when patients were admitted directly to a stroke
centre compared to receiving treatment first at a non-specialist local
hospital.
Conclusion
This
review found that health outcomes are the same for patients who are
transferred directly to a specialist centre and those who are treated at
a non-specialist local hospital before being transferred to a
specialist centre. However, the authors cite poor data and study quality as
major limitations to the generalizability of these findings, and more
evidence is needed to support the current guidelines of transferring all
stroke patients to specialist stroke centres for treatment.
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