http://circoutcomes.ahajournals.org/content/10/8/e003604?cpetoc=
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Abstract
Background—We
explored regional variation in 30-day ischemic stroke mortality and
readmission rates and the extent to which regional differences in
patients, hospitals, healthcare resources, and a quality of care
composite care measure explain the observed variation.
Methods and Results—This
ecological analysis aggregated patient and hospital characteristics
from the Get With The Guidelines–Stroke registry (2007–2011), healthcare
resource data from the Dartmouth Atlas of Health Care (2006), and
Medicare fee-for-service data on 30-day mortality and readmissions
(2007–2011) to the hospital referral region (HRR) level. We used linear
regression to estimate adjusted HRR-level 30-day outcomes, to identify
HRR-level characteristics associated with 30-day outcomes, and to
describe which characteristics explained variation in 30-day outcomes.
The mean adjusted HRR-level 30-day mortality and readmission rates were
10.3% (SD=1.1%) and 13.1% (SD=1.1%), respectively; a modest, negative
correlation (r=−0.17; P=0.003) was found between one
another. Demographics explained more variation in readmissions than
mortality (25% versus 6%), but after accounting for demographics,
comorbidities accounted for more variation in mortality compared with
readmission rates (17% versus 7%). The combination of hospital
characteristics and healthcare resources explained 11% and 16% of the
variance in mortality and readmission rates, beyond patient
characteristics. Most of the regional variation in mortality (65%) and
readmission (50%) rates remained unexplained.
Conclusions—Thirty-day
mortality and readmission rates vary substantially across HRRs and
exhibit an inverse relationship. While regional variation in 30-day
outcomes were explained by patient and hospital factors differently,
much of the regional variation in both outcomes remains unexplained.
- Received January 26, 2017.
- Accepted July 6, 2017.
- © 2017 American Heart Association, Inc.
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