Should be able to be used in stroke rehab if ANYONE in stroke has any innovative functioning brain cells at all. But that will never occur. Stroke brains are fossilized and don't work, which is why they are in the stroke field.
Development of a battery-free ultrasonically powered functional electrical stimulator for movement restoration after paralyzing spinal cord injury
- Monzurul Alam†,
- Shuai Li†,
- Rakib Uddin Ahmed,
- Yat Man Yam,
- Suman Thakur,
- Xiao-Yun Wang,
- Dan Tang,
- Serena Ng and
- Yong-Ping ZhengEmail author
†Contributed equally
Journal of NeuroEngineering and Rehabilitation201916:36
© The Author(s). 2019
- Received: 16 November 2018
- Accepted: 22 February 2019
- Published: 8 March 2019
Abstract
Background
Functional electrical
stimulation (FES) is used to restore movements in paretic limbs after
severe paralyses resulting from neurological injuries such as spinal
cord injury (SCI). Most chronic FES systems utilize an implantable
electrical stimulator to deliver a small electric current to the
targeted muscle or nerve to stimulate muscle contractions. These
implanted stimulators are generally bulky, mainly due to the size of the
batteries. Furthermore, these battery-powered stimulators are required
to be explanted every few years for battery replacement which may result
in surgical failures or infections. Hence, a wireless power transfer
technique is desirable to power these implantable stimulators.
Methods
Conventional wireless power
transduction faces significant challenges for safe and efficient energy
transfer through the skin and deep into the body. Inductive and
electromagnetic power transduction is generally used for very short
distances and may also interfere with other medical measurements such as
X-ray and MRI. To address these issues, we have developed a wireless,
ultrasonically powered, implantable piezoelectric stimulator. The
stimulator is encapsulated with biocompatible materials.
Results
The stimulator is capable of
harvesting a maximum of 5.95 mW electric power at an 8-mm depth under
the skin from an ultrasound beam with about 380 mW/cm2 of
acoustic intensity. The stimulator was implanted in several paraplegic
rats with SCI. Our implanted stimulator successfully induced several
hindlimb muscle contractions and restored leg movement.
Conclusions
A battery-free miniature
(10 mm diameter × 4 mm thickness) implantable stimulator, developed in
the current study is capable of directly stimulating paretic muscles
through external ultrasound signals. The required cost to develop the
stimulator is relatively low as all the components are off the shelf.
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