I don't think stroke survivors give a flying fuck about Motor evoked potential crapola. They want to know whether it produced better recovery results. WELL DID IT?
Interhemispheric Modulation of Dual-Mode, Noninvasive Brain Stimulation on Motor Function
Eunhee Park, MD1, Yun-Hee Kim, MD1, Won Hyuk Chang, MD1, Tae Gun Kwon, MD1, Yong-Il Shin, MD1,2,31Department of Physical and Rehabilitation Medicine, Center for Prevention and Rehabilitation, Heart Vascular and Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul; 2Department of Rehabilitation Medicine, Pusan National University School of Medicine, Yangsan; 3Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea
Objective
To investigate the effects of simultaneous, bihemispheric, dual-mode stimulation using repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) on motor functions and cortical excitability in healthy individuals.
Methods Twenty-five healthy, right-handed volunteers (10 men, 15 women; mean age, 25.5 years) were enrolled. All participants received four randomly arranged, dual-mode, simultaneous stimulations under the following conditions: condition 1, high-frequency rTMS over the right primary motor cortex (M1) and sham tDCS over the left M1; condition 2, high-frequency rTMS over the right M1 and anodal tDCS over the left M1; condition 3, high-frequency rTMS over the right M1 and cathodal tDCS over the left M1; and condition 4, sham rTMS and sham tDCS. The cortical excitability of the right M1 and motor functions of the left hand were assessed before and after each simulation.
Results Motor evoked potential (MEP) amplitudes after stimulation were significantly higher than before stimulation, under the conditions 1 and 2. The MEP amplitude in condition 2 was higher than both conditions 3 and 4, while the MEP amplitude in condition 1 was higher than condition 4. The results of the Purdue Pegboard test and the box and block test showed significant improvement in conditions 1 and 2 after stimulation.
Conclusion Simultaneous stimulation by anodal tDCS over the left M1 with high-frequency rTMS over the right M1 could produce(I would fire people using weasel words like this.) interhemispheric modulation and homeostatic plasticity, which resulted in modulation of cortical excitability and motor functions.
Keywords Bihemispheric stimulation, Transcranial direct current stimulation (tDCS), Transcranial magnetic stimulation (TMS), Interhemispheric modulation, Motor function
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