Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, November 9, 2013

From past experiences to future perspectives: some major points still open in adult neurogenesis

What is your doctor going to learn from this to create a stroke protocol to generate new neurons in your brain?
http://www.frontiersin.org/Journal/abstract/72191
  • 1Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Turin, Italy
  • 2 Dept. of Life Sciences and Systems Biology, Italy
  • 3 Dept. of Veterinary Sciences, Italy
Two decades of investigation on adult neurogenesis yielded an utterly new vision of brain plasticity in mammals. Nevertheless, the ultimate goal of exploiting neurogenic processes for brain repair is still far from being achieved. Starting from this antinomy, the big question is: should be the research field of adult neurogenesis considered as a dead end in the perspective of brain repair, or, alternatively, do we need further efforts directed to better understand this biological process in order to solve the problem? Though neurobiologists do not share the same answer, it is evident that the huge knowledge gathered up to now in the field is not sufficient for granting translation of basic neurobiological research to reparative strategies. In this opinion article we suggest that failure in developing efficacious therapeutic approaches is linked to several unresolved issues in both domains of physiological and lesion-induced neurogenesis. We focus on the role of some aspects (e.g., stem/progenitor cell availability, regenerative capacity, glial cell activation, inflammatory reactions) which can determine the potential for neurogenic plasticity, yet depending on different variables which influence the tissue environment (ages, anatomical regions, homeostatic/pathologic states) and in turn depend on evolutionary constraints linked to the animal species. In our opinion, further investment/investigation directed at filling such existing gaps of knowledge in brain plasticity are needed before a new era for brain repair might be opened.

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