Deans' stroke musings: Gut microbes can help in improving your social life

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, November 7, 2013

Gut microbes can help in improving your social life

Social support is very important in our recovery efforts. What is your doctor doing to support that need?
Like this?

New form of brain plasticity: Study shows how social isolation disrupts myelin production

or this?

Predictors identified for rehospitalization among post-acute stroke patients

Blogger talking about it here;
http://saypeople.com/2013/11/07/microbes-can-help-in-improving-your-social-life-some-related-research-suggestions/#.UnvHC3dYE2k
The original abstract here;
Microbial Symbionts Accelerate Wound Healing via the Neuropeptide Hormone Oxytocin

Abstract

Wound healing capability is inextricably linked with diverse aspects of physical fitness ranging from recovery after minor injuries and surgery to diabetes and some types of cancer. Impact of the microbiome upon the mammalian wound healing process is poorly understood. We discover that supplementing the gut microbiome with lactic acid microbes in drinking water accelerates the wound-healing process to occur in half the time required for matched control animals. Further, we find that Lactobacillus reuteri enhances wound-healing properties through up-regulation of the neuropeptide hormone oxytocin, a factor integral in social bonding and reproduction, by a vagus nerve-mediated pathway. Bacteria-triggered oxytocin serves to activate host CD4+Foxp3+CD25+ immune T regulatory cells conveying transplantable wound healing capacity to naive Rag2-deficient animals. This study determined oxytocin to be a novel component of a multi-directional gut microbe-brain-immune axis, with wound-healing capability as a previously unrecognized output of this axis. We also provide experimental evidence to support long-standing medical traditions associating diet, social practices, and the immune system with efficient recovery after injury, sustained good health, and longevity.
Citation: Poutahidis T, Kearney SM, Levkovich T, Qi P, Varian BJ, et al. (2013) Microbial Symbionts Accelerate Wound Healing via the Neuropeptide Hormone Oxytocin. PLoS ONE 8(10): e78898. doi:10.1371/journal.pone.0078898
Editor: Silvana Gaetani, Sapienza University of Rome, Italy
Received: April 3, 2013; Accepted: September 17, 2013; Published: October 30, 2013
Copyright: © 2013 Poutahidis et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: This work was supported by National Institutes of Health grants P30-ES002109 (pilot project award to SEE and EJA), U01 CA164337 (to SEE and EJA), and RO1CA108854 (to SEE). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.