With our high rate of depression post-stroke, how long will it take before your doctor starts prescribing wine? Don't follow me, I prescribe myself wine on at least a weekly basis, accompanied by lots of social contact and laughter.
http://www.ncbi.nlm.nih.gov/pubmed/23988010
Gea A1,
Beunza JJ,
Estruch R,
Sánchez-Villegas A,
Salas-Salvadó J,
Buil-Cosiales P,
Gómez-Gracia E,
Covas MI,
Corella D,
Fiol M,
Arós F,
Lapetra J,
Lamuela-Raventós RM,
Wärnberg J,
Pintó X,
Serra-Majem L,
Martínez-González MA;
PREDIMED GROUP.
Abstract
BACKGROUND:
Alcoholic
beverages are widely consumed. Depression, the most prevalent mental
disorder worldwide, has been related to alcohol intake. We aimed to
prospectively assess the association between alcohol intake and incident
depression using repeated measurements of alcohol intake.
METHODS:
We
followed-up 5,505 high-risk men and women (55 to 80 y) of the PREDIMED
Trial for up to seven years. Participants were initially free of
depression or a history of depression, and did not have any history of
alcohol-related problems. A 137-item validated food frequency
questionnaire administered by a dietician was repeated annually to
assess alcohol intake. Participants were classified as incident cases of
depression when they reported a new clinical diagnosis of depression,
and/or initiated the use of antidepressant drugs. Cox regression
analyses were fitted over 23,655 person-years.
RESULTS:
Moderate
alcohol intake within the range of 5 to 15 g/day was significantly
associated with lower risk of incident depression (hazard ratio (HR) and
95% confidence interval (95% CI) = 0.72 (0.53 to 0.98) versus
abstainers). Specifically, wine consumption in the range of two to seven
drinks/week was significantly associated with lower rates of depression
(HR (95% CI) = 0.68 (0.47 to 0.98)).
CONCLUSIONS:
Moderate consumption of wine may reduce the incidence of depression, while heavy drinkers seem to be at higher risk.
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