http://nnr.sagepub.com/content/early/2014/11/10/1545968314558599.abstract?&
- Gyrd Thrane, MSc1,2
- Torunn Askim, PhD3,4
- Roland Stock, MSc5
- Bent Indredavik, MD, PhD5
- Ragna Gjone, MSc6
- Anne Erichsen, MSc7
- Audny Anke, MD, PhD1,2
- 1UiT The Arctic University of Norway, Tromsø, Norway
- 2University Hospital of North Norway, Tromsø, Norway
- 3Norwegian University of Science and Technology, Trondheim, Norway
- 4Sør-Trøndelag University College, Trondheim, Norway
- 5Trondheim University Hospital, Norway
- 6Vestfold Hospital Trust, Norway
- 7Oslo University Hospital, Norway
- Gyrd Thrane, MSc, Department of Health and Care Sciences, University of Tromsø, Faculty of Health Sciences, NO-9037 Tromsø, Norway. Email: gyrd.thrane@uit.no
Abstract
Background. There is limited
evidence for the effects of constraint-induced movement therapy (CIMT)
in the early stages of stroke recovery.
Objective. To evaluate the effect of a modified CIMT within 4 weeks poststroke. Methods.
This single-blinded randomized multisite trial investigated the effects
of CIMT in 47 individuals who had experienced a
stroke in the preceding 26 days. Patients were
allocated to a CIMT or a usual care (control) group. The CIMT program
was 3
h/d over 10 consecutive working days, with mitt use
on the unaffected arm for up to 90% of waking hours. The follow-up time
was 6 months. The primary outcome was the Wolf
Motor Function test (WMFT) score. Secondary outcomes were the Fugl-Meyer
upper-extremity
motor score, Nine-Hole Peg test (NHPT) score, the
arm use ratio, and the Stroke Impact Scale. Analyses of covariance with
adjustment for baseline values were used to assess
differences between the groups. Results. After treatment, the
mean timed WMFT score was significantly better in the CIMT group
compared with the control group. Moreover,
posttreatment dexterity, as tested with the NHPT,
was significantly better in the CIMT group, whereas the other test
results
were similar in both the groups. At the 6-month
follow-up, the 2 groups showed no significant difference in arm
impairment,
function, or use in daily activities. Conclusions. Despite a favorable effect of CIMT on timed movement measures immediately after treatment, significant effects were not
found after 6 months.
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