I got nothing useful out of this, so you will have to ask your personal stroke researcher how to use this information. It should be done once by a great stroke association but instead we have fucking failures of stroke associations. And will need to be done for 10 million yearly stroke survivors.
What can be done when mild cognitive impairment occurs?
For 12 weeks, participants receiving GCI participated twice per week in group sessions led by trained instructors, and those receiving HCI completed homework materials 5 days per week. They were assessed at baseline, post intervention (PI) and at the 6-month follow-up. The primary endpoint was the change from baseline to PI in the modified Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-Cog). Results showed that compared to controls (a 0.8-point decrease), subjects receiving GCI (a 2.3-point decrease, p = 0.01) or HCI (a 2.5-point decrease, p = 0.02) reported significant improvements in the modified ADAS-Cog at PI, respectively. These findings were confirmed at 6-month follow-up, where those receiving GCI or HCI still had better scores in the modified ADAS-Cog than controls.
In addition, changes in BDNF levels significantly correlated with the changes in the modified ADAS-Cog in the GCI (r = -0.29, p = 0.02 at PI) and HCI (r = -0.27, p = 0.03 at 6-month follow-up) groups. Authors concluded that an enhanced brain plasticity may be a crucial component of the mechanism underpinning cognitive improvements associated with cognitive interventions.
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