Deans' stroke musings: Prior antithrombotic use is associated with favorable mortality and functional outcomes in acute ischemic stroke

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, July 26, 2016

Prior antithrombotic use is associated with favorable mortality and functional outcomes in acute ischemic stroke

This really is useless, nothing on the amount of the intervention(aspirin size) and nothing on the length of time used. So you will have to do it by the by guess and by golly method just like everything else in stroke.
http://www.mdlinx.com/internal-medicine/medical-news-article/2016/07/26/antiplatelet-agents-antithrombotic-agents-mortality-prognosis/6769817/?
This research was designed to explore the association between prior antithrombotic use with favorable mortality and clinical outcomes in acute ischemic stroke. Findings imply previous antithrombotic therapy was independently associated with improved clinical outcomes after acute ischemic stroke. Guaranteeing the use of antithrombotics in suitable patient populations might be associated with benefits beyond stroke prevention.

Methods

The authors examined the unadjusted and adjusted associations between previous antithrombotic use and clinical outcomes, using data from Get With The Guidelines–Stroke with over half a million acute ischemic strokes recorded between October 2011 and March 2014 (n=540993) from 1661 hospitals across the United States.

Results

As per this study, there were 250104 (46%) stroke patients not receiving any antithrombotic before stroke; of whom approximately 1/3^rd had a documented previous vascular indication.
Patients who were receiving antithrombotics before stroke had better outcomes than those who did not, after controlling for clinical and hospital factors, regardless of whether a previous vascular indication was present or not: adjusted odds ratio (95% confidence intervals) were 0.82 (0.80–0.84) for in–hospital mortality, 1.18 (1.16–1.19) for home as the discharge destination, 1.15 (1.13–1.16) for independent ambulatory status at discharge, and 1.15 (1.12–1.17) for discharge modified Rankin Scale score of 0 or 1.

Go to PubMed Go to Abstract Print Article Summary Cat 2 CME Report