A great stroke association would be analyzing these results to determine the incidence of dementia post-stroke so protocols could be established to prevent dementia. But that won't occur, you are completely fucking on your own. Start hiring your own researchers. Good luck with that.
Incidence of Dementia over Three Decades in the Framingham Heart Study
Abstract
BACKGROUND:
The
prevalence of dementia is expected to soar as the average life
expectancy increases, but recent estimates suggest that the age-specific
incidence of dementia is declining in high-income countries. Temporal
trends are best derived through continuous monitoring of a population
over a long period with the use of consistent diagnostic criteria. We
describe temporal trends in the incidence of dementia over three decades
among participants in the Framingham Heart Study.
METHODS:
Participants
in the Framingham Heart Study have been under surveillance for incident
dementia since 1975. In this analysis, which included 5205 persons 60
years of age or older, we used Cox proportional-hazards models adjusted
for age and sex to determine the 5-year incidence of dementia during
each of four epochs. We also explored the interactions between epoch and
age, sex, apolipoprotein E ε4 status, and educational level, and we
examined the effects of these interactions, as well as the effects of
vascular risk factors and cardiovascular disease, on temporal trends.
RESULTS:
The
5-year age- and sex-adjusted cumulative hazard rates for dementia were
3.6 per 100 persons during the first epoch (late 1970s and early 1980s),
2.8 per 100 persons during the second epoch (late 1980s and early
1990s), 2.2 per 100 persons during the third epoch (late 1990s and early
2000s), and 2.0 per 100 persons during the fourth epoch (late 2000s and
early 2010s). Relative to the incidence during the first epoch, the
incidence declined by 22%, 38%, and 44% during the second, third, and
fourth epochs, respectively. This risk reduction was observed only among
persons who had at least a high school diploma (hazard ratio, 0.77; 95%
confidence interval, 0.67 to 0.88). The prevalence of most vascular
risk factors (except obesity and diabetes) and the risk of dementia
associated with stroke, atrial fibrillation, or heart failure have
decreased over time, but none of these trends completely explain the
decrease in the incidence of dementia.
CONCLUSIONS:
Among
participants in the Framingham Heart Study, the incidence of dementia
has declined over the course of three decades. The factors contributing
to this decline have not been completely identified. (Funded by the
National Institutes of Health.).
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