Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 11846 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Deans' stroke musings
Changing stroke rehab and research worldwide now.Time is Brain!Just think of all thetrillions and trillions of neuronsthateach daybecause there areeffective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It's quite disgusting that this information is not available from every stroke association and doctors group. My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html
Tuesday, November 8, 2016
Low Serum Levels of Brain-Derived Neurotrophic Factor Were Associated with Poor Short-Term Functional Outcome and Mortality in Acute Ischemic Stroke
brain-derived neurotrophic factor (BDNF) has been highlighted as being a
key regulator of rehabilitation-induced recovery after stroke. The aim
of this study was to evaluate the association between serum levels of
BDNF and functional outcome and mortality events in a 3-month follow-up
study in a cohort of patients with an acute ischemic stroke (AIS). From
January 2015 to December 2015, consecutive first-ever AIS patients
admitted to the Department of Emergency of our hospital were identified.
Serum BDNF levels were measured at admission. Functional outcome was
evaluated at 3 months using the modified Rankin scale (m-Rankin). We
used logistic regression models to assess the relationship between BDNF
levels and functional outcome or mortality. In this study, 204 patients
were included. Patients with poor outcomes and non-survivors had
significantly lower BDNF levels on admission (P < 0.0001
all). Multivariate logistic regression analysis adjusted for common
risk factors showed that BDNF levels in the lowest interquartile (≤1st
9.2 ng/ml) was an independent predictor of functional outcome (odds
ratios [OR] = 3.75; 95 % confidence interval [CI], 2.43–8.12) and
mortality (OR = 4.04; 95 % CI, 2.07–9.14). The area under the receiver
operating characteristic curve of BDNF was 0.77 (95 % CI, 0.70–0.84) for
functional outcome and 0.79 (95 % CI, 0.71–0.86) for mortality. The
findings indicated that low serum levels of BDNF at admission were
significantly associated with poor short-term functional outcome and
mortality, suggesting that BDNF may serve as a biomarker of poor
function outcome after stroke.