Total red meat intake of ≥ 0.5 servings/d does not negatively influence cardiovascular disease risk factors: A systemically searched meta-analysis of randomized controlled trials

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Total red meat intake of ≥ 0.5 servings/d does not negatively influence cardiovascular disease risk factors: A systemically searched meta-analysis of randomized controlled trials

American Journal of Clinical Nutrition, 11/30/2016 O'Connor LE, et al.

In this systematically searched meta–analysis, researchers evaluate the impacts of consuming ≥ 0.5 or <0.5 servings of total red meat/d on CVD risk factors [blood total cholesterol (TC), LDL cholesterol, HDL cholesterol, triglycerides, ratio of TC to HDL cholesterol (TC:HDL), and systolic and diastolic blood pressures (SBP and DBP, respectively)]. They speculated that the intake of ≥0.5 servings of total red meat/d would have a negative affect these CVD risk factors. The outcomes from this systematically sought meta–analysis of RCTs support the idea that the intake of ≥0.5 servings of total red meat/d does not impact blood lipids and lipoproteins or blood pressures.

Methods

• From 24 qualified RCTs, 2 researchers independently screened 945 studies from PubMed, Cochrane Library, and Scopus databases and extracted data.
• Inclusion criteria were 1) RCT, 2) subjects aged ≥19 y, 3) intake of ≥ 0.5 or <0.5 total red meat servings/d [35 g (1.25 ounces)], and 4) reporting ≥1 CVD risk factor.
• They played out an adjusted 2–factor nested ANOVA mixed–effects model procedure on the postintervention values of TC, LDL cholesterol, HDL cholesterol, TC:HDL cholesterol, triglycerides, SBP, and DBP; ascertained general impact sizes of change values; and utilized a repeated–measures ANOVA to evaluate pre– to postintervention changes.

Results

• Red meat consumption did not influence lipid–lipoprotein profiles or blood pressure values postintervention (P > 0.05) or changes over time [weighted mean difference (95% CI): –0.01 mmol/L (–0.08, 0.06 mmol/L), 0.02 mmol/L (–0.05, 0.08 mmol/L), 0.03 mmol/L (–0.01, 0.07 mmol/L), and 0.04 mmol/L (–0.02, 0.10 mmol/L) mmol/L; –0.08 mm Hg (–0.26, 0.11 mm Hg); and –1.0 mm Hg (–2.4, 0.78 mm Hg) and 0.1 mm Hg (–1.2, 1.5 mm Hg) for TC, LDL cholesterol, HDL cholesterol, triglycerides, TC:HDL cholesterol, SBP, and DBP, respectively].
• Among all subjects, TC, LDL cholesterol, HDL cholesterol, TC:HDL cholesterol, triglycerides, and DBP, but not SBP, diminished over time (P < 0.05). 
• Total gobbledegook I'm sure done on purpose so it looks important.

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