Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, November 26, 2016

Stroke risk factors are sex-specific

There are 14 stroke risk calculators here so you can challenge your doctor about which one is best.
Or you can check out this newest idea, even though they don't tell you what risk calculator they used:
http://www.healio.com/internal-medicine/cardiology/news/online/%7Bbcc24a45-8485-48fc-949c-601e37119ce7%7D/stroke-risk-factors-are-sex-specific?
?Individualized stroke risk assessments that consider female- and male- specific characteristics can improve accuracy of risk scores, according to findings published in JAMA Neurology.
“The incidence of stroke is higher in men than in women,” Michiel H.F. Poorthuis, MD, from the department of neurology and neurosurgery at the University Medical Center Utrecht, the Netherlands, and colleagues wrote. “The influence of sex-specific risk factors on stroke incidence and mortality is largely unknown.”
Poorthuis and colleagues performed a systematic review and meta-analysis of observational studies published between Jan. 1, 1985, and Jan. 26, 2015, that evaluated sex-specific factors and their association with stroke. They used a generic variance-based, random-effects method to pool estimates. Seventy longitudinal studies and eight case-control studies involving 10,187,540 patients met inclusion criteria.
The researchers found an increased risk for ischemic stroke in women who had any hypertensive disorder in pregnancy, such as gestational hypertension, preeclampsia or eclampsia had (pooled RR = 1.8; 95% CI, 1.49-2.18). Women with late menopause occurring at the age of at least 55 years (pooled RR = 2.24; 95% CI, 1.19-4.21) and a history of gestational hypertension (pooled RR = 5.08; 95% CI, 1.8-14.34) had an increased risk for hemorrhagic stroke. There was an increased risk for any stroke in women with a history of oophorectomy (pooled RR = 1.42; 95%CI, 1.34-1.5), any hypertensive disorder in pregnancy (pooled RR = 1.63; 95%CI, 1.52-1.75), preeclampsia or eclampsia (pooled RR = 1.54; 95%CI, 1.39-1.7), gestational hypertension (pooled RR = 1.51; 95%CI, 1.27-1.8), preterm delivery (pooled RR = 1.62; 95%CI, 1.46-1.79) and stillbirth (pooled RR = 1.86; 95%CI, 1.15-3.02).
Conversely, there was a reduced risk for any stroke for women who had a hysterectomy (pooled RR = 0.88; 95%CI, 0.85-0.9). In women with a history of gestational hypertension the pooled RR of stroke mortality was 1.57 (95% CI, 1.04-2.39).
Men with a history of androgen deprivation therapy had an increased risk for ischemic stroke (pooled RR = 1.19; 95% CI, 1.05-1.34) and any stroke (pooled RR =1.21; 95%CI, 1.06-1.37). In addition, men who had an orchiectomy had an increased risk for ischemic stroke (pooled RR = 1.21; 95% CI, 1-1.46) and men with erectile dysfunction had an increased risk for any stroke (pooled RR = 1.35 [95%CI, 1.18-1.53]).
“These sex-specific variables could be helpful in identifying specific patient groups with an increased risk of stroke, and individual risk factors should be considered in recommendations on primary prevention of stroke and in secondary prevention of stroke in patients with manifest cardiovascular disease,” Poorthuis and colleagues wrote. – by Alaina Tedesco
Disclosure: Poorthuis reports no relevant financial disclosures. Please see full study for complete list of all other authors’ disclosures.

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