Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, November 26, 2016

Association Between Sarcopenia(Muscle loss) and Cognitive Impairment: A Systematic Review and Meta-Analysis

What protocols is your doctor using to make sure you have no muscle loss? Hemiplegia is not an excuse for allowing this atrophy.  This goes back to cause and effect, if your doctor has valid interventions for these 5 causes of neuronal cascade of death, then you would have much fewer dead and damaged neurons allowing you to move around much better. Does your doctor even understand this concept? And no followup studies will be done so we will never know exactly the relationship and the urgency to solve this for stroke survivors.
 http://www.jamda.com/article/S1525-8610%2816%2930428-5/fulltext?rss=yes

Ke-Vin Chang, MD, PhD
,
Tsai-Hsuan Hsu, MS
,
Wei-Ting Wu, MD
,
Kuo-Chin Huang, MD, PhD
,
Der-Sheng Han, MD, PhDcorrespondencePress enter key for correspondence information
DOI: http://dx.doi.org/10.1016/j.jamda.2016.09.013
|

Abstract

Background

Sarcopenia, a gradual loss of muscle mass and function, has been associated with poor health outcomes. Its correlation with another age-related degenerative process, impaired cognition, remains uncertain. This meta-analysis aimed to determine whether there is an association between sarcopenia and cognitive impairment.

Methods

PubMed and Scopus were searched for observational studies that investigated the association between sarcopenia and cognitive dysfunction. Participants’ demographics and measurements, definition of sarcopenia, and tools for evaluating cognitive function were retrieved. The correlations between sarcopenia and cognitive impairment were expressed as crude and adjusted odds ratios with 95% confidence intervals (CIs).

Results

Seven cross-sectional studies comprising 5994 participants were included. The crude and adjusted odds ratios were 2.926 (95% CI, 2.297–3.728) and 2.246 (95% CI, 1.210–4.168), respectively. The subgroup analysis showed that different target populations and sex specificity did not significantly modify the association, whereas the tools for evaluating cognitive function and modalities for measuring body composition did.

Conclusions

Sarcopenia was independently associated with cognitive impairment. Future cohort studies are warranted to clarify the causal correlation. The inclusion of relevant biomarkers and functional measurements is also recommended to elucidate the underlying biological mechanism.

Keywords:

Sarcopenia, cognition, dementia, muscle, aging

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The study was funded by the research funding of the Community and Geriatric Research Center, National Taiwan University Hospital, Bei-Hu Branch.
The authors declare no conflicts of interest.
© 2016 AMDA - The Society for Post-Acute and Long-Term Care Medicine.

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