Deans' stroke musings: Position-cortical coherence as a marker of afferent pathway integrity early poststroke: A prospective cohort study

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, June 11, 2020

Position-cortical coherence as a marker of afferent pathway integrity early poststroke: A prospective cohort study

I can see zero use for this measurement because there is nothing to improve the afferent pathway integrity. Useless.

Position-cortical coherence as a marker of afferent pathway integrity early poststroke: A prospective cohort study

Neurorehabilitation and Neural Repair (NNR) , Volume 34(4) , Pgs. 344-359.

NARIC Accession Number: J83568. What's this?
ISSN: 1545-9683.
Author(s): Zandvliet, Sarah B. ; van Wegen, Erwin E. H. ; Campfens, S. Floor ; van der Kooij, Herman ; Kwakkel, Gert ; Meskers, Carel G. M..
Publication Year: 2020.
Number of Pages: 16.
Abstract:
Study investigated the longitudinal construct validity of position-cortical coherence (PCC), that is, the agreement between mechanically evoked wrist perturbations and electroencephalography (EEG), as a measure of afferent pathway integrity. PCC was measured serially in 48 patients after a first-ever ischemic stroke in addition to Fugl-Meyer motor assessment of the upper extremity (FM-UE) and Nottingham Sensory Assessment hand-finger subscores (EmNSA-HF), within 3 and at 5, 12, and 26 weeks poststroke. Changes in PCC over time, represented by percentage presence of PCC (%PCC), mean amplitude of PCC over the affected (Amp-A) and nonaffected hemisphere (Amp-N) and a lateralization index (L-index), were analyzed, as well as their association with FM-UE and EmNSA-HF. Patients were retrospectively categorized based on FM-UE score at baseline and 26 weeks poststroke into high- and low-baseline recoverers and non-recoverers. %PCC increased from baseline to 12 weeks poststroke, which was no longer significant after adjusting for EmNSA-HF and FM-UE. A significant positive association was found between %PCC, Amp-A, and EmNSA-HF. Low-baseline recoverers showed longitudinally significantly higher %PCC than high-baseline recoverers. This study demonstrated the longitudinal construct validity of %PCC and Amp-A as a measure of afferent pathway integrity. A high %PCC in low-baseline recoverers suggests that this measure also contains information on cortical excitability. Use of PCC as an EEG-based measure to address the role of somatosensory integrity to motor recovery poststroke requires further attention.
Descriptor Terms: ELECTROPHYSIOLOGY, LIMBS, MOTOR SKILLS, STROKE.

Can this document be ordered through NARIC's document delivery service*?: Y.
Get this Document: https://pubmed.ncbi.nlm.nih.gov/32129142/.

Citation: Zandvliet, Sarah B. , van Wegen, Erwin E. H. , Campfens, S. Floor , van der Kooij, Herman , Kwakkel, Gert , Meskers, Carel G. M.. (2020). Position-cortical coherence as a marker of afferent pathway integrity early poststroke: A prospective cohort study. Neurorehabilitation and Neural Repair (NNR) , 34(4), Pgs. 344-359. Retrieved 6/11/2020, from REHABDATA database.