Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Sunday, June 14, 2020

Gender gap in stroke treatment narrowing

The obvious solution is to have EXACT stroke diagnosis protocols that lead directly to EXACT stroke treatment protocols, followed by EXACT stroke rehab protocols leading to 100% recovery. If your doctor, stroke hospital, stroke association do not have these as goals they ALL NEED TO BE FIRED. 

Gender gap in stroke treatment narrowing

Previous studies have shown that men are more likely than women to receive treatment with IV thrombolysis for acute ischemic stroke. However, new research published in Neurology, the medical journal of the American Academy of Neurology, suggests the treatment gap appears to be narrowing.
“Thrombolysis is the most effective treatment we have to prevent the potentially life altering disability that can occur following a stroke,” Mathew Reeves, PhD, professor of epidemiology and biostatistics at Michigan State University in East Lansing, told Healio Primary Care. “Any treatment gap found for women is to their detriment.”

Quote from Reeves on stroke treatment gap in women
In 2009, a meta-analysis of 18 studies showed that women had 30% lower odds of receiving IV recombinant tissue plasminogen activator (rtPA) for acute ischemic stroke compared with men.
“Over the life course more women than men suffer a stroke, women are older when they have their stroke and have greater disability afterwards,” Reeves said. “Thrombolysis can help reduce these higher rates of disability in women ... if they receive it.”
To determine if the treatment gap persisted in recent years, Reeves and colleagues conducted a systematic review and meta-analysis of 24 studies with sex-specific information on IV rtPA treatment for acute ischemic stroke published from 2008 through 2018. Of those, 17 studies included treatment rates for all patients with acute ischemic stroke.
The results showed that women had 13% lower odds of receiving IV rtPA treatment than men (OR = 0.87; 95% CI, 0.82-0.93), according to Reeves and colleagues. However, the researchers noted that there was substantial variability between the studies.
An analysis of seven studies that included data on a subgroup of patients who were eligible for IV rtPA also found lower odds for women receiving treatment (summary OR = 0.95; 95% CI, 0.88-1.02), although this was not statistically significant.
To estimate the treatment gap over time, the researchers developed a time trend using the 17 studies with data on all patients with acute ischemic stroke and 16 studies from the 2009 meta-analysis. The researchers categorized these 33 studies into four time periods based on publication date and found that the linear trend across the summary ORs was not statistically significant.
However, when directly comparing summary ORs, Reeves and colleagues determined that women’s odds of receiving treatment was significantly different between 2000 to 2004 (OR = 0.73; 95% CI, 0.67-0.8) and 2014 to 2018 (OR = 0.9; 95% CI, 0.84-0.97).
“We need to continue to monitor and study this treatment gap, as well as others,” Reeves said.
He noted that in addition to increasing public education on stroke, efforts are needed to “redesign stroke systems of care to improve the identification, transportation, work-up and treatment of stroke while continuing to closely exam treatment rates in women.”
“We want to see thrombolysis treatment rates increase for everyone — men and women,” Reeves said. “Right now, treatment rates are still too low.”
References:
American Academy of Neurology. Treatment gap between men and women for stroke may have narrowed. https://www.aan.com/PressRoom/Home/PressRelease/3799. Accessed June 10, 2020.

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