Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, December 15, 2020

Acupuncture for the Treatment of Alzheimer's Disease: An Overview of Systematic Reviews

Oh God.

Impossible to have effects except as a placebo. Energy meridians have never been proven to exist.
No mechanism of action is possible. 

But if you believe, have at it, recognizing these possible side effects;

 The latest here:

Acupuncture for the Treatment of Alzheimer's Disease: An Overview of Systematic Reviews

Jinke Huang1, Min Shen1, Xiaohui Qin2, Manli Wu1, Simin Liang1 and Yong Huang3*
  • 1The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China
  • 2Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China
  • 3School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, China

Background: Acupuncture may be an effective complementary treatment for Alzheimer's disease (AD). The aim of this study was to summarize the evidence provided by systematic reviews (SRs)/meta-analyses (MAs) on the effect of acupuncture on AD.

Methods: Eight electronic databases were searched from their inception until October 19, 2020. The methodological quality, reporting quality, and risk of bias of the included SRs were assessed by the Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR-2), the Risk of Bias in Systematic Reviews (ROBIS) tool, and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Moreover, the evidence quality of the outcome measures was assessed by the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE).

Results: Eleven SRs/MAs met all inclusion criteria. According to the results of the AMSTAR-2, all included reviews were rated critically as being of low quality. With PRISMA, the reporting checklist was relatively complete, but some reporting weaknesses remained in the topics of the protocol and registration, search strategy, risk of bias, additional analyses, and funding. Based on the ROBIS tool, only two SRs/MAs had a low risk of bias. With the GRADE system, no high-quality evidence was found, and only seven outcomes provided moderate-quality evidence. Among the downgraded factors, the risk of bias within the original trials was ranked first, followed by inconsistency, imprecision, and publication bias.

Conclusions: Acupuncture is a promising complementary treatment for AD. However, due to the low quality of the SRs/MAs supporting these results, high-quality studies with rigorous study designs and larger samples are needed before widespread recommendations can be made.

Introduction

Alzheimer's disease (AD) is a common progressive degenerative encephalopathy characterized by cognitive impairment, declining memory, emotional changes, and a language barrier (McKhann et al., 1984). AD seriously affects the physical health and quality of life of patients and places a heavy burden on families and society (Xu et al., 2017). With the extension of the average life expectancy of the population, the incidence of AD is increasing annually; the number of patients worldwide is currently as high as 24 million, which is expected to increase 4-fold by 2050 (Reitz and Mayeux, 2014). Currently, no medication can prevent, halt, or reverse the progression of AD. The clinical drugs approved by the Food and Drug Administration (FDA) for AD only have modest symptomatic effects (Atri et al., 2008) and have been related to many adverse reactions (Tampi and Dyck, 2007). Hence, some patients choose complementary and alternative medicine to treat AD in an effort to improve their quality of life. Worldwide, acupuncture has been accepted as a popular and safe complementary therapy (Bodeker et al., 2005), and it has been widely used to treat AD by physicians aiming to reduce the side effects of medication and to increase its therapeutic effectiveness.

Systematic reviews (SRs)/meta-analyses (MAs) are important tools to guide evidence-based clinical practice, and they have been widely used in various medical fields in recent years. However, with the increasing number of SRs/MAs, their quality is uneven, and their conclusions on the same topic of SR/MAs are often contradictory; therefore, the clinical evidence they provide has been criticized. A systematic overview of SRs/MAs is a relatively new approach for synthesizing the outcomes from multiple SRs/MAs, evaluating their quality and attempting to address any inconsistent outcomes. The objective of our study was to critically assess the scientific quality of relevant SRs/MAs regarding the application of acupuncture in the treatment of PD using a systematic overview.

 
Posted by at
Labels: , ,

No comments:

Post a Comment

Subscribe to: Post Comments (Atom)