Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, December 26, 2020

Trials in Sleep Apnea and Stroke Learning From the Past to Direct Future Approaches

Well first you need a protocol to identify that sleep apnea exists, my stroke doctors never found my sleep apnea. Then you need to come up with something other than CPAP that treats sleep apnea. I couldn't sleep at all with a CPAP.  If you don't realize that CPAP adherence is a problem that needs a different solution then you really don't belong solving stroke problems.  Status quo is not acceptable.

 

Trials in Sleep Apnea and Stroke: Learning From the Past to Direct Future Approaches

Originally publishedhttps://doi.org/10.1161/STROKEAHA.120.031709Stroke. ;0

Few randomized controlled trials have evaluated the effectiveness of continuous positive airway pressure (CPAP) in reducing recurrent vascular events and mortality in poststroke obstructive sleep apnea (OSA). To date, results have been mixed, most studies were underpowered and definitive conclusions are not available. Using lessons learned from prior negative trials in stroke, we reappraise prior randomized controlled trials that examined the use of CPAP in treating poststroke OSA and propose the following considerations: (1) Intervention-based changes, such as ensuring that patients are using CPAP for at least 4 hours per night (eg, through use of improvements in CPAP technology that make it easier for patients to use), as well as considering alternative treatment strategies for poststroke OSA; (2) Population-based changes (ie, including stroke patients with severe and symptomatic OSA and CPAP noncompliers); and (3) Changes to timing of intervention and follow-up (ie, early initiation of CPAP therapy within the first 48 hours of stroke and long-term follow-up calculated in accordance with sample size to ensure adequate power). Given the burden of vascular morbidity and mortality in stroke patients with OSA, there is a strong need to learn from past negative trials and explore innovative stroke prevention strategies to improve stroke-free survival.

Footnotes

*Drs Boulos and Dharmakulaseelan are joint first authors.

For Sources of Funding and Disclosures, see page 371.

Correspondence to: Mark I. Boulos, MD, Sunnybrook Health Sciences Centre, Room A455 - 2075 Bayview Ave, Toronto, ON M4N 3M5 Canada. Email
 

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