Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, August 9, 2025

Characterising Long-Term Depressive Symptoms Post-brain Injury: A Systematic Review of Symptom Trajectory Groups and Their Predictors

Isn't your competent? doctor preventing depression and anxiety by having 100% recovery protocols? NO?  So, you DON'T have a functioning stroke doctor, do you? PREDICTIONS DO NOTHING!

I'd fire everybody involved in this crapola!

You want your doctor to prevent post stroke depression and anxiety the proper way; 100% RECOVERY PROTOCOLS!  Not any after the fact intervention.

Post stroke depression(33% chance).

Post stroke anxiety(20% chance).  


Characterising Long-Term Depressive Symptoms Post-brain Injury: A Systematic Review of Symptom Trajectory Groups and Their Predictors


Review
  • Open access
  • Published: 

  • Abstract

    This systematic review investigates the long-term trajectories of depressive symptoms in individuals with acquired brain injury (ABI) and identifies factors predicting group membership in these trajectories. The review follows the PRISMA guidelines and is registered on the International Platform of Registered Systematic Review and Meta-analysis Protocols (INPLASY-2023–11-0013). A comprehensive search of MEDLINE, PSYCINFO, EMBASE, CINHALPlus, ScienceDirect, Scopus, and Web of Science identified peer-reviewed studies published in English on adults aged 16 and above with an ABI diagnosis. Studies were included if they used a validated depression measure, had at least three assessment points, and applied group-based trajectory modelling. Exclusion criteria included studies focusing on neurodegenerative or neurodevelopmental disorders, or solely on treatments. The methodological quality was assessed using Joanna Briggs’ critical appraisal tool. The review synthesised data from ten studies involving 13,205 participants (average age 51.38 years, 55.86% male). Four depressive symptom trajectory groups were identified with varying prevalence: stable low (68%), persistent high (13%), increasing (20%), and decreasing (11%). Several key predictors including sex, age, injury severity, and education emerged as significant predictors of group membership in the persistent highincreasing, and decreasing depressive groups. However, variability in study methodologies and sample compositions posed challenges to direct comparison. Nonetheless, the review underscores the importance of long-term monitoring and the development of tailored interventions, as depression can manifest or intensify years post-injury. Understanding depressive symptom trajectories could help create personalised interventions, improving quality of life for those with depression after ABI.

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