For your doctor to relate to your condition. For a while there I was kicking myself for stopping an aspirin regime during my 6 day canoe trip directly prior to my event.
http://www.strokejournal.org/article/PIIS1052305711001169/abstract?rss=yes
Background
The widespread use of aspirin-driven vascular
prevention strategies does not impede the occurrence of first and
recurrent ischemic strokes in numerous subjects. It is not clear what
factors are associated with aspirin failure beyond the functional
diagnosis of
aspirin resistance in selected subjects. Current management
guidelines provide little or no recommendations on the proper strategy
for subjects who had a stroke while receiving aspirin. We assessed
clinical features of subjects who had a first or recurrent stroke while
taking aspirin.
Methods
We studied demographic
characteristics, vascular risk factors, stroke subtypes, and concomitant
medication use in subjects with first or recurrent ischemic strokes.
Patients receiving antiplatelet medications other than aspirin and/or
oral anticoagulants were excluded from this analysis.
Results
Seven
hundred and nine patients with first (n = 552) or recurrent (n = 157)
ischemic stroke were evaluated. Aspirin was being taken by 29% of first
and 48% of recurrent stroke subjects. There was a higher prevalence of
hypertension, hypercholesterolemia, and smoking in aspirin users with
first and recurrent stroke (
P < .05). Diabetes and coronary artery disease were more frequent in aspirin users with first ischemic strokes (
P
< .003), but not in those who had recurrent ischemic strokes.
Aspirin users were more likely to be also receiving statins and
antihypertensive drugs (
P < .001).
Conclusions
Aspirin
failure in ischemic stroke prevention may exceed functional resistance
to aspirin and could be associated with a higher prevalence of lacunar
stroke, comorbidities, and/or adverse interactions with other drugs.
These patients may require a different approach regarding prevention
strategies.
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