Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, June 14, 2014

Asynchronous therapy restores motor control by rewiring of the rat corticospinal tract after stroke

You are going to have to demand your doctor contact the researcher and find out what growth-promoting immunotherapy was used and whether there is any downside to using it in humans. But you doctor won't even do that simple thing, they are paid regardless of how well you recover. Damned easy to do, look at that, an author email address.
http://www.sciencemag.org/content/344/6189/1250.abstract
  1. M. E. Schwab1,2,*
+ Author Affiliations
  1. 1Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
  2. 2Brain Research Institute, University of Zurich, Zurich, Switzerland.
  3. 3Computer Vision Group, Heidelberg Collaboratory for Image Processing and Interdisciplinary Center for Scientific Computing (IWR), University of Heidelberg, Heidelberg, Germany.
  4. 4Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland.
  5. 5National Institute for Physiological Sciences, National Institute of Natural Sciences Myodaiji, Okazaki, Japan.
  1. *Corresponding author. E-mail: schwab@hifo.uzh.ch (M.E.S.); wahl@hifo.uzh.ch (A.S.W.)
The brain exhibits limited capacity for spontaneous restoration of lost motor functions after stroke. Rehabilitation is the prevailing clinical approach to augment functional recovery, but the scientific basis is poorly understood. Here, we show nearly full recovery of skilled forelimb functions in rats with large strokes when a growth-promoting immunotherapy against a neurite growth–inhibitory protein was applied to boost the sprouting of new fibers, before stabilizing the newly formed circuits by intensive training. In contrast, early high-intensity training during the growth phase destroyed the effect and led to aberrant fiber patterns. Pharmacogenetic experiments identified a subset of corticospinal fibers originating in the intact half of the forebrain, side-switching in the spinal cord to newly innervate the impaired limb and restore skilled motor function.

From another writeup on it.
The “medication” is made up of antibodies against the so-called Nogo protein that prevents nerve growth and was discovered by Schwab and his colleagues nearly 20 years ago.

No comments:

Post a Comment