Deans' stroke musings: Globorisk - New score predicts heart disease and stroke risk for anyone in world aged over 40

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, March 30, 2015

Globorisk - New score predicts heart disease and stroke risk for anyone in world aged over 40

You can probably compare this to all the other ones because your doctor probably won't.
My risk when I had my stroke was nil because none of these have any way to measure plaque buildup and the risk of that plaque rupturing. And none will determine if your aneurysms are ready to burst But I bet your doctor doesn't know anything either. This covers all the ones I've written about.

Stroke Riskometers

I can't find the actual test so I can't determine if mine was predictable with this new one
The newest one here:
http://www.alphagalileo.org/ViewItem.aspx?ItemId=151120&CultureCode=en
For the first time, scientists have developed a new risk score that can predict the 10-year risk of developing heart disease or having a stroke in persons aged 40 years or older in any world country.
The research is published in The Lancet Diabetes & Endocrinology journal, and was led by Dr Goodarz Danaei, Assistant Professor of Global Health at the Harvard T. H. Chan School of Public Health in Boston, USA.
Danaei and colleagues developed, validated, and evaluated the new score, called Globorisk, using data from eight cohort studies [1], including more than 50 000 participants. Unlike previous risk scores, Globorisk can be updated to fit local conditions and risk factor levels in different countries using routinely available information.
Dr Danaei explains, “Globorisk is an important advance in the field of global cardiovascular disease prevention. Until now, most prediction scores were developed using a single cohort study and were never validated for accuracy in national populations for low- and middle-income countries. Therefore, clinicians and public health policy makers in these countries were left without a reliable tool to predict cardiovascular risk in their patients, community, or country.”[2]
Globorisk measures cardiovascular risk in individuals aged 40 or older by factoring in the person’s smoking status, blood pressure, diabetes status, and total cholesterol level, whilst adjusting for the effects of sex and age on cardiovascular disease between countries.

The researchers recalibrated and applied their risk score to 11 countries from different world regions [3], using data from recent national health surveys to replace the average age-and-sex risk factor levels in each country and incorporating cardiovascular disease death rates for each age-and-sex group. They developed country-specific risk charts for predicting individuals’ risk of cardiovascular disease (see figure 4 pages 7-14), and country-specific assessments of the 10-year cardiovascular disease burden (see figure 5 page 15).
They estimate that the proportion of people at high risk (10% or higher) of having a fatal heart attack or stroke within 10 years is higher in low- and middle-income countries (eg, China and Mexico) compared with high-income countries (eg, South Korea, Spain, and Denmark). For example, in China around a third of men and women (nearly 170 million aged between 40 and 84 years) have a high 10-year risk of dying from a cardiovascular event compared with only 5–10% of men and women in Spain and Denmark (see figure 5 page 15).
According to Dr Danaei, “Globorisk can be used to identify individuals at high risk of developing cardiovascular disease who are most likely to benefit from lifestyle changes or preventive drug treatment. Moreover, by estimating the number of people who have a high risk in any given country we have more chance of accurately measuring progress towards the WHO target of 50% coverage of multidrug treatment and counselling for people aged 40 years and older at high risk of cardiovascular disease.” [2]
Karel Moons from the Utrecht University Medical Center in the Netherlands and Ewoud Schuit from the same centre and from Stanford University in the USA, both authors of a linked Comment, say, “A next step would be to quantify the effects, on a population level, of introducing in these countries the Globorisk model combined with subsequent risk-based preventative management. These quantifications might further help, and indeed convince, decision-makers across the world to decide on wide-scale introduction of prediction models and risk-based management for cardiovascular disease.” [2]