Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, September 29, 2015

Second Trial of Chelation Therapy Wins Early Support

This is only interesting in the possible prevention of cardiovascular events in persons with diabetes. So don't go down this route unless your doctor agrees. Alternative medicine usually is quackery until it is proven to work, then it is no longer alternative, just regular medicine.
http://www.medpagetoday.com/Cardiology/CardioBrief/53754?xid=nl_mpt_DHE_2015-09-29&eun=g424561d0r
The National Institutes of Health is giving money to support the planning of a second trial to test the potential role of chelation therapy in treating patients with myocardial infarction.
The first Trial to Assess Chelation Therapy (TACT) was extremely controversial. It was funded by the NIH more than a dozen years ago as part of an initiative to study alternative medicine. Chelation therapy with EDTA to remove heavy metals from the blood in order to treat coronary disease has been around -- and provoked criticism -- since the 1950s. Until TACT the mainstream medical community had completely dismissed chelation therapy.
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TACT was a double-blind trial testing active or placebo infusions of chelation in 1,708 stable patients with a history of MI. In the chelation group there was a modest but statistically significant reduction in the primary endpoint of the trial -- the composite of death, MI, stroke, coronary revascularization, or hospitalization for angina (26% vs 30%, HR 0.82, CI 0.69-0.99, P=0.035).
The rationale for TACT2 is based on the observation in the earlier study that nearly all the benefit occurred in the subgroup of 633 patients who had diabetes. For this group there was a highly significant 41% reduction in the primary endpoint (25% vs 38%, HR 0.59, CI 0.44-0.79, P<0.001), as well as a 43% reduction in overall mortality and a 52% reduction in recurrent MI.
To followup on these findings the National Center for Complementary and Integrative Health (NCCIH) has now awarded $800,000 to initiate planning for TACT2. "A subgroup analysis of the original trial results suggests major benefit in diabetics with cardiovascular disease. The disease burden in this group of patients is devastating, so a replication of these findings is of some urgency," said Josephine P. Briggs, the Director of the National Center for Complementary and Integrative Health, in an NIH press release.
"The hallmark of science is the ability to replicate results," said the study chairman, Gervasio Lamas, MD, of the Mount Sinai Medical Center in Miami Beach, Fla. "Unless we can show a consistent effect across the two TACT Trials and establish a similar mechanism to deliver the treatment safely, it will be difficult for chelation to enter the mainstream of other cardiovascular therapies."
Eugene Braunwald, MD, gave a strong endorsement to TACT2 in the press release: "The results of TACT were both surprising and intriguing. I am very pleased that TACT2 is building on these findings to determine if they can be replicated in diabetic patients who have experienced a myocardial infarction -- a particularly high risk group of patients in need of effective therapy."

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