Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, July 12, 2016

Improving Motor Corticothalamic Communication After Stroke Using Real-Time fMRI Connectivity-Based Neurofeedback

Once again this needs to be written up as a publicly available stroke protocol. That way it can be improved upon and actually help survivors. This research publishing model is totally fucking useless for survivors.  This is a job for that great stroke association.
http://nnr.sagepub.com/content/30/7/671?etoc
  1. Sook-Lei Liew, PhD, OTR/L1,2
  2. Mohit Rana, PhD3,4,5
  3. Sonja Cornelsen, Dipl. Psych6
  4. Marcos Fortunato de Barros Filho, MD7
  5. Niels Birbaumer, PhD4,8
  6. Ranganatha Sitaram, PhD3,4,5
  7. Leonardo G. Cohen, MD1
  8. Surjo R. Soekadar, MD4,7
  1. 1Human Cortical Physiology and Neurorehabilitation Section, NINDS, NIH, Bethesda, MD, USA
  2. 2Chan Division of Occupational Science and Occupational Therapy, Division of Physical Therapy and Biokinesiology, Department of Neurology, University of Southern California, Los Angeles, CA, USA
  3. 3Institute for Medical and Biological Engineering, and Department of Psychiatry and Section of Neuroscience, Schools of Engineering, Medicine and Biology, Pontificia Universidad Católica de Chile, Santiago, Chile
  4. 4Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Germany
  5. 5Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA
  6. 6Center for Neurology, Division of Neuropsychology, Hertie-Institute for Clinical Brain Research, Eberhard Karls University, Tübingen, Germany
  7. 7Applied Neurotechnology Lab, Department of Psychiatry and Psychotherapy, University Hospital of Tübingen, Tübingen, Germany
  8. 8IRCSS, Ospedale San Camillo, Venice, Italy
  1. Sook-Lei Liew, PhD, OTR/L, USC Neural Plasticity and Neurorehabilitation Laboratory, 1540 Alcazar St, CHP 133 MC 9003, Los Angeles, CA 90089-0080, USA. Email: sliew@usc.edu
  2. Surjo R. Soekadar, MD, Applied Neurotechnology Lab, University Hospital of Tübingen, Calwerstr. 14, 72076 Tübingen, Germany. Email: surjo.soekadar@uni-tuebingen.de

Abstract

Background. Two thirds of stroke survivors experience motor impairment resulting in long-term disability. The anatomical substrate is often the disruption of cortico-subcortical pathways. It has been proposed that reestablishment of cortico-subcortical communication relates to functional recovery. 
Objective. In this study, we applied a novel training protocol to augment ipsilesional cortico-subcortical connectivity after stroke. Chronic stroke patients with severe motor impairment were provided online feedback of blood-oxygenation level dependent signal connectivity between cortical and subcortical regions critical for motor function using real-time functional magnetic resonance imaging neurofeedback.  
Results. In this proof of principle study, 3 out of 4 patients learned to voluntarily modulate cortico-subcortical connectivity as intended.  
Conclusions. Our results document for the first time the feasibility and safety for patients with chronic stroke and severe motor impairment to self-regulate and augment ipsilesional cortico-subcortical connectivity through neurofeedback using real-time functional magnetic resonance imaging.

No comments:

Post a Comment