Antioxidant Reduces Risk for 2nd Stroke, Heart Attack

Now YOU just need to find the protocol for this and train your doctor in its use.  Not the other way around. Has your doctor EVER  put ANY clinical research into practice? This is one of the few things I got from the NSA that was worth it.

Antioxidant Reduces Risk for 2nd Stroke, Heart Attack

Posted by Lynn Bronikowski Sep 27 2018

 

Healthcare professionals have long known that in the months after a heart attack or stroke, patients are more likely to have another attack or stroke.
Now a study published in the Journal of the American College of Cardiology explains what happens inside blood vessels to increase stroke and heart attack risk—and suggests a new way to treat it.
Researchers found that heart attacks in mice caused inflammatory cells and platelets to more easily stick to the inner lining of arteries throughout the body—particularly where there was already plaque, according to the study’s writeup. As a result, these sticky cells and platelets caused plaque to become unstable and contribute to blood clots that led to another stroke or heart attack.
But the study found treating mice that had experienced a stroke or heart attack with the powerful antioxidant apocynin cut plaque buildup in half and lowered inflammation to pre-attack levels.
"Knowing that newer forms of antioxidants such as apocynin can lower the risk of a second heart attack or stroke gives us a new treatment to explore and could one day help reduce heart attacks and strokes," said the study’s author, Jonathan R. Lindner, M.D., a professor of cardiovascular medicine at the OHSU School of Medicine.
Lindner penned the research paper with colleagues from OHSU, Scripps Research Institute and Bloodworks NW.
The researchers discovered the sticky cells and platelets by using unique forms of ultrasound imaging they developed to view molecules on the lining of blood vessels.
This research could help explain why the recent Canakinumab Anti-inflammatory Thrombosis Outcomes Study, also known as the CANTOS clinical trial, found an anti-inflammatory drug already approved to treat juvenile arthritis also reduced the risk of a second heart attack in trial participants by 15 percent.
Lindner and his colleagues are further studying how the relative stickiness of remote arteries affects the risks for additional heart attacks and strokes and are also evaluating new therapies beyond antioxidants.
The study was supported by the National Institutes of Health and the Swiss National Science Foundation.

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