Use the labels in the right column to find what you want. Or you can go thru them one by one, there are only 16456 posts. Searching is done in the search box in upper left corner. I blog on anything to do with stroke.DO NOT DO ANYTHING SUGGESTED HERE AS I AM NOT MEDICALLY TRAINED, YOUR DOCTOR IS, LISTEN TO THEM. BUT I BET THEY DON'T KNOW HOW TO GET YOU 100% RECOVERED. I DON'T EITHER, BUT HAVE PLENTY OF QUESTIONS FOR YOUR DOCTOR TO ANSWER.
Changing stroke rehab and research worldwide now.Time is Brain!Just think of all thetrillions and trillions of neuronsthateach daybecause there areNOeffective hyperacute therapies besides tPA(only 12% effective). I have 493 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.
What this blog is for:
Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group. My back ground story is here:http://oc1dean.blogspot.com/2010/11/my-background-story_8.html
Monday, October 22, 2018
Interaction between warfarin and cannabis
Be careful out there. I guess I may have to wait until I'm off warfarin after my next stroke before I start rehabbing with marijuana.
This article has been accepted for publication and undergone
full peer review but has not been through the copyediting, typesetting,
pagination and proofreading process, which may lead to differences
between this version and the Version of Record. Please cite this article
as doi: 10.1111/bcpt.13152
Delta‐9‐tetrahydrocannabinol (THC), the main psychoactive
cannabinoid in cannabis, may inhibit the cytochrome P450 enzyme CYP2C9.
Consequently, cannabis use might infer a risk of drug‐drug interaction
with substrates for this enzyme, which includes drugs known to have a
narrow therapeutic window. In this study, we describe a case report of a
27‐year‐old man treated with warfarin due to mechanical heart valve
replacement who presented with elevated international normalized ratio
(INR) value (INR = 4.6) following recreational cannabis use. We
conducted a review of the available literature, using the PubMed and
EMBASE databases while following PRISMA guidelines. Following screening
of 85 articles, three eligible articles were identified, including one in vitro study and two case reports. The in vitro
study indicated that THC inhibits the CYP2C9‐mediated metabolism of
warfarin. One case study reported of a man who on two occasions of
increased marijuana use experienced INR values above 10 as well as
bleeding. The other case study reported of a patient who initiated
treatment with a liquid formulation of cannabidiol (CBD) for the
management of epilepsy, ultimately necessitating a 30% reduction in
warfarin dose to maintain therapeutic INR values. The available,
although sparse, data suggest that use of cannabinoids increase INR
values in patients receiving warfarin. Until further data are available,
we suggest patients receiving warfarin be warned against cannabis
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