Since we as stroke survivors may be more likely to get Alzheimers your doctor will need to get this article and see if there is any way a prevention protocol can be inferred from it.
Ask your doctor.
https://www.thieme-connect.com/ejournals/abstract/10.1055/s-0032-1315377
Abstract
Recent studies suggest that by the middle of this century, as many as
14 million Americans will have Alzheimerʼs disease, creating an
enormous strain on families, the health care system and the federal
budget. There are still widespread misconceptions about issues related
to the prevention and/or treatment of disease pathogenesis, leaving us
unprepared to deal with the disease. To address these challenges,
several therapeutic approaches are currently under investigation, mainly
in an attempt to delay disease onset and eventually slow down its
progression. Recent epidemiological evidence has implicated the
protective role of dietary polyphenols from grape products against
Alzheimerʼs disease. Furthermore, experimental evidence supports the
hypothesis that certain bioactive grape-derived polyphenols may protect
against Alzheimerʼs disease-type cognitive deterioration, in part by
interfering with the generation and assembly of
β-amyloid
peptides into neurotoxic oligomeric aggregated species. Brain-targeting
polyphenols have been shown to significantly reduce the generation of
β-amyloid
peptides in primary cortico-hippocampal neuron cultures, and
preliminary results indicate that they may influence neuronal synaptic
plasticity. Recent evidence has also implicated the role of certain
grape-derived preparations in beneficially modulating tau
neuropathology, including reducing tau aggregation. Studies suggest that
dietary polyphenolics may benefit Alzheimerʼs disease by modulating
multiple disease-modifying modalities, both
β-amyloid-dependent
and independent mechanisms, and provide impetus for the development of
polyphenolic compounds for Alzheimerʼs disease prevention and/or
therapy.
No comments:
Post a Comment