Deans' stroke musings: Hypothermia as a clinical neuroprotectant

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Tuesday, December 9, 2014

Hypothermia as a clinical neuroprotectant

You can have your doctor compare this to the earlier ones and see if they need to update a stroke protocol on this.
The previous ones here;

Mild Hypothermia After Intravenous Thrombolysis in Patients With Acute Stroke

Moderate Hypothermia Inhibits Brain Inflammation and Attenuates Stroke-Induced Immunodepression in Rats

Mild Hypothermia Reduces Tissue Plasminogen Activator-Related Hemorrhage and Blood Brain Barrier Disruption After Experimental Stroke

A Decade of Reversal: An Analysis of 146 Contradicted Medical Practices

The latest one here:

Hypothermia as a clinical neuroprotectant

Physical Medicine and Rehabilitation Clinics of North America , Volume 25(3) , Pgs. 519-529.

NARIC Accession Number: J69551. What's this?
ISSN: 1047-9651.
Author(s): Sherman, Andrew L.; Wang, Michael Y..
Publication Year: 2014.
Number of Pages: 11.
Abstract: Article reviews the mechanisms by which therapeutic hypothermia (TH) mitigates secondary neurologic injury, the clinical scenarios where TH is being applied, and selected published studies using TH for central nervous system neuroprotection. TH is defined simply as the reduction of mean body core temperature to create some medical benefit. Hypothermia induces a variety of human responses to combat the hypothermia. Applying hypothermia for the purposes of neuroprotection started nearly 100 years ago, initially used to treat brain abscesses. Applied TH has evolved over the years and, with modern techniques, has become more practical to use. TH has been used to provide neuroprotection and minimize tissue injury in several conditions, including but are not limited to, spinal cord injury (SCI), traumatic brain injury, stroke, cardiac arrest, burn injury, and subarachnoid hemorrhage. TH can help after SCI at both phases of injury: the primary phase that leads to direct spinal cord tissue damage and the secondary injury phase that leads to apoptosis and further spinal cord damage. Initial pilot studies suggest that applying TH might lead to improved functional outcome. However, larger multicenter trials are needed to prove these findings.
Descriptor Terms: INTERVENTION, NEUROLOGY, PHYSICAL MEDICINE, PHYSIOLOGY, SPINAL CORD INJURIES.

Can this document be ordered through NARIC's document delivery service*?: Y.

Citation: Sherman, Andrew L., Wang, Michael Y.. (2014). Hypothermia as a clinical neuroprotectant. Physical Medicine and Rehabilitation Clinics of North America, 25(3), Pgs. 519-529. Retrieved 12/9/2014, from REHABDATA database.