Scientists Discover How Resveratrol Provides Health Benefits

Do not start drinking red wine because of this. There is absolutely no information available as to what a decent dosage might be and your attempts to find out on your own are fraught with danger to yourself and others. I'm not drinking red wine for the health benefits, I'm drinking it for the social connections.  Do not follow my lead, I'm sure there is not a stroke doctor in the world that would agree that drinking red wine is good for you.
http://www.biosciencetechnology.com/news/2014/12/scientists-discover-how-resveratrol-provides-health-benefits?
Scientists at The Scripps Research Institute (TSRI) have found that resveratrol, the red-wine ingredient once touted as an elixir of youth, powerfully activates an evolutionarily ancient stress response in human cells. The finding should dispel much of the mystery and controversy about how resveratrol really works.
“This stress response represents a layer of biology that has been largely overlooked, and resveratrol turns out to activate it at much lower concentrations than those used in prior studies,” said senior investigator Paul Schimmel, professor and member of the Skaggs Institute for Chemical Biology at TSRI.
“With these findings we have a new, fundamental mechanism for the known beneficial effects of resveratrol,” said lead author Mathew Sajish, a senior research associate in the Schimmel laboratory.
The discovery is reported in the advance online edition of Nature.
Resveratrol is a compound produced in grapes, cacao beans, Japanese knotweed and some other plants in response to stresses including infection, drought and ultraviolet radiation. It has attracted widespread scientific and popular interest over the past decade, as researchers have reported that it extended lifespan and prevented diabetes in obese mice and vastly increased the stamina of ordinary mice running on wheels.
More recently, though, scientists in this field have disagreed about the signaling pathways resveratrol activates to promote health, calling into question some of resveratrol’s supposed health benefits—particularly given the unrealistically high doses used in some experiments.

Schimmel and his laboratory also are searching for molecules that can activate the TyrRS stress response pathway even more potently than resveratrol does.

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