http://www.ncbi.nlm.nih.gov/pubmed/20645831
Abstract
This
study investigated some pharmacological properties of virgin coconut
oil (VCO), the natural pure oil from coconut [Cocos nucifera Linn
(Palmae)] milk, which was prepared without using chemical or high-heat
treatment. The anti-inflammatory, analgesic, and antipyretic effects of
VCO were assessed. In acute inflammatory models, VCO showed moderate
anti-inflammatory effects on ethyl phenylpropiolate-induced ear edema in
rats, and carrageenin- and arachidonic acid-induced paw edema. VCO
exhibited an inhibitory effect on chronic inflammation by reducing the
transudative weight, granuloma formation, and serum alkaline phosphatase
activity. VCO also showed a moderate analgesic effect on the acetic
acid-induced writhing response as well as an antipyretic effect in
yeast-induced hyperthermia. The results obtained suggest
anti-inflammatory, analgesic, and antipyretic properties of VCO.
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