Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, December 24, 2014

Statins and the risk of herpes zoster: A population-based cohort study

I have no clue if this is alarming or not. Ask your up-to-date doctor for clarification on whether you should worry about this.
http://cid.oxfordjournals.org/content/early/2013/12/02/cid.cit745.short?rss=1
  1. Tara Gomes2,3,4,6
+ Author Affiliations
  1. 1Department of Family and Community Medicine, St Michael's Hospital
  2. 2Keenan Research Centre of the Li Ka Shing Knowledge Institute, St Michael's Hospital
  3. 3University of Toronto
  4. 4Institute for Clinical Evaluative Sciences
  5. 5Sunnybrook Research Institute
  6. 6Applied Health Research Centre, St Michael's Hospital, Toronto, Ontario, Canada
  7. 7King Saud University, Riyadh, Saudi Arabia
  1. Correspondence: Tony Antoniou, PhD, 410 Sherbourne St, 4th Floor, Toronto, ON M4X 1K2, Canada (tantoniou@smh.ca).

Abstract

Background.  Statins are widely used lipid-lowering drugs with immunomodulatory properties that may favor reactivation of latent varicella-zoster virus infection. However, whether statins increase the risk of herpes zoster is unknown.
Methods. We conducted a population-based retrospective cohort study of Ontario residents aged ≥66 years between 1 April 1997 and 31 March 2010 to examine the association between statin use and incidence of herpes zoster. We used propensity score matching to ensure similarity between users and nonusers of statins, and Cox proportional hazard models to assess differences in outcomes between study groups. To test the specificity of our findings, we examined the association between statin exposure and knee arthroplasty.
Results. During the 13-year study period, we matched 494 651 individuals treated with a statin to an equal number of untreated individuals. In the main analysis, the rate of herpes zoster was higher among users of statins relative to nonusers of these drugs (13.25 vs 11.71 per 1000 person-years, respectively; hazard ratio [HR], 1.13; 95% confidence interval [CI], 1.10–1.17). The attributable fraction of exposed individuals was 11.6%. In a prespecified analysis, we found a similar risk of herpes zoster among statin users in the subgroup of patients with diabetes (HR, 1.18; 95% CI, 1.09–1.27). As expected, we found no association between statin use and knee arthroplasty (HR, 1.04; 95% CI, .99–1.09).
Conclusions. Among older patients, treatment with statins is associated with a small but significantly increased risk of herpes zoster.


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