http://www.jneuroengrehab.com/content/12/1/88/abstract
Journal of NeuroEngineering and Rehabilitation 2015, 12:88
doi:10.1186/s12984-015-0078-5
Published: 26 September 2015
Published: 26 September 2015
Abstract
Background
We evaluated the feasibility of an augmented robotics-assisted tilt table (RATT) for
incremental cardiopulmonary exercise testing (CPET) and exercise training in dependent-ambulatory
stroke patients.
Methods
Stroke patients (Functional Ambulation Category ≤ 3) underwent familiarization, an
incremental exercise test (IET) and a constant load test (CLT) on separate days. A
RATT equipped with force sensors in the thigh cuffs, a work rate estimation algorithm
and real-time visual feedback to guide the exercise work rate was used. Feasibility
assessment considered technical feasibility, patient tolerability, and cardiopulmonary
responsiveness.
Results
Eight patients (4 female) aged 58.3 ± 9.2 years (mean ± SD) were recruited and all
completed the study. For IETs, peak oxygen uptake (V'O
2peak
), peak heart rate (HR
peak
) and peak work rate (WR
peak
) were 11.9 ± 4.0 ml/kg/min (45 % of predicted V'O
2max
), 117 ± 32 beats/min (72 % of predicted HR
max
) and 22.5 ± 13.0 W, respectively. Peak ratings of perceived exertion (RPE) were on
the range "hard" to "very hard". All 8 patients reached their limit of functional
capacity in terms of either their cardiopulmonary or neuromuscular performance.
A ventilatory threshold (VT) was identified in 7 patients and a respiratory compensation
point (RCP) in 6 patients: mean V'O
2
at VT and RCP was 8.9 and 10.7 ml/kg/min, respectively, which represent 75 % (VT)
and 85 % (RCP) of mean V'O
2peak
. Incremental CPET provided sufficient information to satisfy the responsiveness criteria
and identification of key outcomes in all 8 patients.
For CLTs, mean steady-state V'O
2
was 6.9 ml/kg/min (49 % of V'O
2
reserve), mean HR was 90 beats/min (56 % of HR
max
), RPEs were > 2, and all patients maintained the active work rate for 10 min: these
values meet recommended intensity levels for bouts of training.
Conclusions
The augmented RATT is deemed feasible for incremental cardiopulmonary exercise testing
and exercise training in dependent-ambulatory stroke patients: the approach was found
to be technically implementable, acceptable to the patients, and it showed substantial
cardiopulmonary responsiveness. This work has clinical implications for patients with
severe disability who otherwise are not able to be tested.
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