Deans' stroke musings: The Inflammatory Potential of the Diet is Directly Associated with Incident Depressive Symptoms Among French Adults

Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Thursday, June 6, 2019

The Inflammatory Potential of the Diet is Directly Associated with Incident Depressive Symptoms Among French Adults

Useless, no explanation of what this diet is as compared to the French paradox.

The French paradox: lessons for other countries - NCBI

The French Diet Is Le Bullshit - The Daily Beast

The Inflammatory Potential of the Diet is Directly Associated with Incident Depressive Symptoms Among French Adults

Moufidath Adjibade Cédric Lemogne Mathilde Touvier Serge Hercberg Pilar Galan Karen E Assmann Chantal Julia Emmanuelle Kesse-Guyot

The Journal of Nutrition, nxz045, https://doi.org/10.1093/jn/nxz045

Published:

01 June 2019

Article history

ABSTRACT

Background

Low-grade chronic inflammation has been suggested to play a substantial role in the etiology of depression; however, studies on the prospective association between the inflammatory potential of the diet and depression are limited.

Objective

The aim of this study was to investigate the association between the inflammatory potential of the diet (measured using the Alternate Dietary Inflammatory Index, ADII) and incident depressive symptoms. We also tested the potential modulating effect of sex, age, BMI, and lifestyle indicators.

Methods

The study sample consisted of 26,730 participants (aged 18–86 y) from the NutriNet-Santé study. Baseline ADII was computed using repeated 24-h dietary records collected during the first 2 y of the follow-up. Incident cases of depressive symptoms were defined by a Center for Epidemiologic Studies Depression scale ≥17 for men and ≥23 for women at least once during follow-up. HR and 95% CI were estimated using multivariable Cox proportional hazards models.

Results

A total of 2221 incident cases of depressive symptoms were identified over a mean follow-up of 5.4 y. After accounting for a wide range of potential confounders, the highest quartile of the ADII was associated with a 15% (95% CI: 2, 31) increase in the risk of depressive symptoms compared with the lowest quartile. In the stratified analyses, associations were statistically significant only among women (HR_{quartile4 vs. quartile1}: 1.19; 95% CI: 1.02, 1.37), middle-age adults (HR_{quartile4 vs. quartile1}: 1.16; 95% CI: 1.00, 1.35), and participants with a BMI ≥25 (HR_{quartile4 vs. quartile1}: 1.29; 95% CI: 1.04, 1.60).

Conclusions

Overall, a proinflammatory diet was associated with a higher risk of depressive symptoms, especially among women, middle-age adults, and participants with overweight or obesity. These findings contribute to the increasing scientific evidence showing a detrimental role of the proinflammatory diet. The NutriNet-Santé study is registered at clinicaltrials.gov as NCT03335644.

mental health, depression, diet, inflammation, prospective study