A half-assed study since they did NOTHING to determine the best way to increase cerebral perfusion. Survivors don't care about biomarkers or trajectory, they are useless in creating recovery.
Study may lead to new approaches to treating reading deficits after stroke
A team of New Jersey stroke researchers has linked recovery of
reading and language competence with cerebral blood flow in the left
reading network. Their findings may contribute to new approaches to
identifying and treating reading deficits after stroke. The open access
article, "Cerebral perfusion of the left reading network predicts
recovery of reading in subacute to chronic stroke" (doi: https:/
Despite the fundamental role of reading ability in everyday living, little research has been conducted on patterns of reading recovery after stroke, or the development of interventions to improve reading outcomes. In this study of left-brain stroke, a team of New Jersey scientists examined patterns of cerebral perfusion bilaterally, including left and right networks of brain areas important for healthy reading, the area surrounding the stroke lesion, and the corresponding contralateral area.
They enrolled 31 participants during inpatient rehabilitation, within 5 weeks of left-sided stroke. All underwent functional magnetic resonance imaging, psychometric testing, neurological examination and tests for phonological, orthographic and semantic impairments. Fifteen participants had follow-up studies at 3 months post stroke. Analysis of data from the subacute and chronic phases showed that recovery of reading and language competence correlated with increases in cerebral blood flow in the left reading network.
Despite the fundamental role of reading ability in everyday living, little research has been conducted on patterns of reading recovery after stroke, or the development of interventions to improve reading outcomes. In this study of left-brain stroke, a team of New Jersey scientists examined patterns of cerebral perfusion bilaterally, including left and right networks of brain areas important for healthy reading, the area surrounding the stroke lesion, and the corresponding contralateral area.
They enrolled 31 participants during inpatient rehabilitation, within 5 weeks of left-sided stroke. All underwent functional magnetic resonance imaging, psychometric testing, neurological examination and tests for phonological, orthographic and semantic impairments. Fifteen participants had follow-up studies at 3 months post stroke. Analysis of data from the subacute and chronic phases showed that recovery of reading and language competence correlated with increases in cerebral blood flow in the left reading network.
Our findings support the utility of cerebral perfusion as a biomarker for recovery after stroke and indicate that early reperfusion of the left reading network is essential to reading performance. We also found that increased perfusion of the right reading network correlated with worse reading performance, which challenges the belief that this increased activity is a necessary transition in the recovery process.The team plans future studies of larger populations, with inclusion of additional time points in order to better define the trajectory of recovery after stroke. "Reading deficits hinder the ability to participate fully in rehabilitation, to return to work, and function effectively at home and in the community," Dr. Boukrina remarked. "Pursuing this avenue of research will help us discover ways to restore function and improve outcomes for individuals recovering from left-brain stroke."
Olga Boukrina, PhD, Research Scientist at the Center for Stroke Rehabilitation Research at Kessler Foundation
Source:
Journal reference:
Boukrina, O. et al. (2019) Cerebral perfusion of the left reading network predicts recovery of reading in subacute to chronic stroke. Human Brain Mapping. doi.org/10.1002/hbm.24773
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