Research progress in the use of botulinum toxin type a for post-stroke spasticity rehabilitation: a narrative review

More useless crapola that gets us no closer to curing spasticity!

You'll want spasticity cured when you are the 1 in 4 per WHO that has a stroke! And then it will be too late! I shouldn't hope schadenfreude hits you with spasticity, but I'm not that good of a person! So I hope like hell you suffer spasticity, just as much as Dr. William M. Landau with his absolutely idiotic opinions on spasticity!  

His statement from here:

Spasticity After Stroke: Why Bother? Aug. 2004 

The latest here:

 Research progress in the use of botulinum toxin type a for post-stroke spasticity rehabilitation: a narrative review

Zongjun Zhu,Yuanyuan Guan Ya Wang Article: 2521427 Received 26 Oct 2024 Accepted 27 May 2025 Published online: 23 Jun 2025 Cite this article 

Abstract

Background 

Stroke is a leading cause of long-term disability and death worldwide. Spasticity after stroke seriously affects patients’ quality of life. If this state persists for a long time, it will lead to severe joint atrophy, reduced motor coordination, and even permanent disability. Therefore, clinical research has focused on the treatment of spasticity and the recovery of motor function after stroke.AimThe aim of this paper is to explore the use of botulinum toxin type A in the rehabilitation of spasticity after stroke and to provide a theoretical basis for optimizing rehabilitation strategies, highlighting its potential value in reducing spasticity and improving motor function.

Method

This article reviews the latest research progress on the application of BTX-A in spasticity after stroke, discusses the potential and challenges of BTX-A in reducing spasticity and improving motor function in patients with stroke.

Result

Botulinum toxin type A (BTX-A) is a local muscle paralytic agent that has received extensive attention in recent years for its application in reducing muscle spasticity and promoting post-stroke rehabilitation.

Conclusion

This article confirms that botulinum toxin type A has a significant clinical effect in treating muscle spasticity after stroke and also helps improve motor function restoration in patients. Studies have shown that botulinum toxin type A injections are effective in reducing spasticity(NOT GOOD ENOUGH! It's not a cure, so then it failed! Survivors hate failure!) and, when combined with rehabilitation training, can facilitate the recovery of motor function in post-stroke patients. Therefore, botulinum toxin type A has a broad application prospect in the rehabilitation of post-stroke spasticity.

KEY MESSAGES

• The application of botulinum toxin type A (BTX-A) in post-stroke rehabilitation primarily focuses on reducing muscle spasticity and improving motor function.

• Spasticity is a common clinical manifestation of damage to the upper motor neurons. It is caused by the increased excitability of gamma motor neurons and manifests as excessive involuntary muscle contraction. Its causes include cerebral palsy, stroke, traumatic brain injury, multiple sclerosis, brain or spinal cord tumours, and spinal cord injuries